摘要
Abstract
Objective :To investigate the clinical effect of acupuncture combined with salmeterol triamcinolone in the treatment of acute exacerbation of bronchial asthma (BA) and its effect on lung function ,serum inflammatory response ,and T lymphocyte subsets .Methods :The 128 acute exacerbation patients who were enrolled in the study were divided into two groups .The control group was treated with salmeterol monohydrate inhaler ,the observation group was treated with acupuncture combined with salmeterol monohydrate inhaler .The changes in lung function pa-rameters (FEV1,FVC ,PEF) ,serum inflammatory factors (IFN-,IL-8 ,IL-4) ,and T lymphocyte subsets (CD3+, CD4+,CD8+,and CD4+ /CD8+) before and after treatment were compared in the two groups ;the clinical manifes-tation rate and total effective rate in two groups was counted .Results :After treatment ,the FEV1,FVC ,PEF val-ues ,serum inflammatory cytokines ,and T lymphocyte subsets CD3+,CD4+,and CD4+ /CD8+ values were signifi-cantly increased in both groups (P＜0 .05) ,the levels of serum inflammatory cytokines IL-8 ,IL-4 and CD8+ in T lymphocyte subsets were significantly lower (P＜0 .05).Compared with the control group ,the changes of lung func-tion ,serum inflammatory factors and T lymphocyte subsets were more obvious in the observation group (P＜0 .05). The clinical display control rate of the observed group was 71 .88%,the total effective rate was 96 .88%,and the control group was 46 .88% and 82 .81% ,respectively .There was a significant difference of the clinical manifestation rate and total effective rate between two groups (P＜0 .05).Conclusion :Acupuncture combined with salmeterol was effective in controlling clinical symptoms of patients with acute exacerbation of BA ,improving lung function ,inhibi-ting body inflammatory response ,and improving immunity .The curative effect is significantly better than that of salmeterol.关键词
哮喘/针灸疗法/支气管/穴,大椎/穴,膻中Key words
Asthma/acupuncture-moxibustion/Bronchi/Point GV14(Dazhui)/Point CV17(Tanzhong)分类
医药卫生
