中国临床药理学杂志2018,Vol.34Issue(20):2395-2397,3.DOI:10.13699/j.cnki.1001-6821.2018.20.001
常规方法联用络酸梭菌活菌片对肝硬化患者血浆胆碱酯酶与白蛋白水平的影响
Effect of clostridium butyricum tablets combined with conventional therapy on the levels of cholinesterase and albumin in patients with liver cirrhosis
摘要
Abstract
Objective To investigate the effect of Clostridium butyricum tablets combined with conventional therapy on the cholinesterase levels and albumin ( ALB) levels in patients with liver cirrhosis.Methods The 236 patients with liver cirrhosis from October 2016 to February 2018 in the Department of Gastroenterology of our hospital were selected as the study subjects.The patients were divided into the treatment group and the control group.The patients in the treatment group were given 2 g Clostridium butyricum tablets orally ,on the basis of general symptomatic treatment,3 times per day for two weeks ;the patients in the control group were stan-dard treatment.The plasma cholinesterase , ALB levels were determined by automatic analyzer.Results The cholinesterase levels in the control group and the treatment group were ( 2.87 ±1.82 ), (7.94 ±2.45) U· L-1, respectively; the ALB levels in the 2 groups were (34.02 ±3.26),(47.63 ±4.05) g· L-1,respectively;comparison between the two groups , the difference was significant ( all P <0.05 ) . Conclusion Clostridium butyricum tablets can significantly increase plasma cholinesterase and ALB levels in patients with liver cirrhosis .关键词
肝硬化/益生菌制剂/胆碱酯酶/白蛋白Key words
liver cirrhosis/Clostridium butyricum tablets/cholinesterase/albumin分类
医药卫生引用本文复制引用
樊慧,赵乃阔,张正安,胡庆军,胡新俊..常规方法联用络酸梭菌活菌片对肝硬化患者血浆胆碱酯酶与白蛋白水平的影响[J].中国临床药理学杂志,2018,34(20):2395-2397,3.基金项目
国家自然科学基金资助项目(81600512) (81600512)