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新型胰高血糖素样肽-1类似物—索马鲁肽

张新丽 丁发明 尹茂山

中国临床药理学杂志2018,Vol.34Issue(20):2456-2460,5.
中国临床药理学杂志2018,Vol.34Issue(20):2456-2460,5.DOI:10.13699/j.cnki.1001-6821.2018.20.018

新型胰高血糖素样肽-1类似物—索马鲁肽

A new glucagon-like peptide-1 analogues-Semaglutide

张新丽 1丁发明 2尹茂山2

作者信息

  • 1. 青岛市黄岛区中心医院,山东 青岛266555
  • 2. 国家食品药品监督管理总局 药品审评中心,北京 100022
  • 折叠

摘要

Abstract

The glucagon-like peptide-1 (GLP-1) receptor agonist has been a well-received peptide product in the field of diabetes treatment .Semaglutide is a long-term GLP -1 agent, approved in December, 2017 by US Food and Drug Admins-tration(FDA).This article reviewed the pharmaceutical information , pharmacology and toxicology and clinical trial data of somaglutide , and commented on its efficacy and safety specially.We hope to provide reference for doctors and patients .

关键词

索马鲁肽/2型糖尿病/胰高血糖素样肽1

Key words

Semaglutide/type 2 diabetes mellitus/glucagon-like peptide-1

分类

医药卫生

引用本文复制引用

张新丽,丁发明,尹茂山..新型胰高血糖素样肽-1类似物—索马鲁肽[J].中国临床药理学杂志,2018,34(20):2456-2460,5.

中国临床药理学杂志

OA北大核心CSCDCSTPCD

1001-6821

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