中国临床药理学杂志2018,Vol.34Issue(20):2465-2468,4.DOI:10.13699/j.cnki.1001-6821.2018.20.020
微小RNA介导的药物对转运体调控作用的研究进展
Research status of microRNA mediated drug regulation of transporter and metabolizing enzymes
摘要
Abstract
MicroRNAs,a family of endogenous non -coding RNAs, are known for their critical role in regulating the expression of target genes through complementary binding to the 3'non-coding region of the target gene mRNA.Drugs indirectly affect drug metabolism by regulating the expression of microRNAs that affect transporters .This article systemati-cally described the research progress and mechanism of microRNA media-ted drug regulation of transporters .关键词
微小RNA/药物转运体/调控Key words
microRNA/drug transporter/regulation分类
医药卫生引用本文复制引用
丁薇,熊玉卿..微小RNA介导的药物对转运体调控作用的研究进展[J].中国临床药理学杂志,2018,34(20):2465-2468,4.基金项目
国家自然科学基金资助项目(81673506) (81673506)