中国医学创新2018，Vol.15Issue(28)：5-10,6.DOI:10.3969/j.issn.1674-4985.2018.28.002
血管内超声虚拟组织学成像在诊断颈动脉狭窄斑块性质与狭窄程度相关性的价值分析
Value of Intravascular Ultrasound Virtual Histology Imaging in Diagnosis of Carotid Plaque and Degree of Stenosis
摘要
Abstract
Objective:To investigate the diagnostic value of the characteristics of carotid stenotic plaques and the degree of stenosis by intravascular ultrasound virtual histological imaging (VH-IVUS).Method:We selected our hospital carotid stenosis from June 2015 to June 2017,thirty patients were included in the study.After IVUS examination,we identified the nature of carotid artery stenosis and the degree of stenosis.According to the degree of luminal stenosis,they were divided into mild stenosis group(stenosis degree≤50%),moderate stenosis group(stenosis degree 50%-69%) and severe stenosis group (stenosis degree≥70%).The correlation between carotid artery stenosis and plaque properties was analyzed.Result:Three groups of narrow lumen area,plaque area and plaque load were more and more heavy(P<0.05),while the cross-sectional area of outer elastic membrane was smaller and smaller(P<0.05).Severe stenosis group had larger fibrous tissue area(P>0.05),while mild stenosis group had more calcified tissue area and necrotic core area(P<0.05),and the proportion of fibrous tissue in three groups of stenosis plaques were higher and higher(P<0.05).The proportion of calcified tissue and necrotic core were getting smaller and smaller(P<0.05).The correlation analysis showed that the degree of lumen stenosis was positively correlated with the percentage of fibrous tissue(r=0.694,P=0.003),negatively correlated with calcified tissue(r=-0.375,P=0.011) and the percentage of necrotic core(r=-0.348,P=0.015).In the mild stenosis group,fibrous fibrous atheromatous plaque(TCFA) and calcified fibrin atheromatous plaque(CaTCFA) were dominated.Conclusion:VH-IVUS can provide a basis for analyzing the properties of carotid plaque and can be used to determine the degree of plaque stenosis and the nature of plaque,and has a certain value in the diagnosis of the relationship between plaque properties and stenosis.关键词
血管内超声/虚拟组织学成像/颈动脉斑块性质/颈动脉狭窄Key words
Intravascular ultrasound/Virtual histological imaging/Properties of carotid plaques/Carotid stenosis引用本文复制引用
赖穗翩,陈钜涛,黎冠东,彭宇程,伍振富,叶杰明..血管内超声虚拟组织学成像在诊断颈动脉狭窄斑块性质与狭窄程度相关性的价值分析[J].中国医学创新,2018,15(28):5-10,6.基金项目
江门市医疗卫生领域科技计划项目(2015002) （2015002）
