中国医学创新2018，Vol.15Issue(28)：56-59,4.DOI:10.3969/j.issn.1674-4985.2018.28.015
2007-2017年儿童川崎病流行病学临床特征及并发冠状动脉病变危险因素调查分析
Clinical Characteristics and Risk Factors of Coronary Artery Disease in Children with Kawasaki Disease from 2007 to 2017
摘要
Abstract
Objective:To investigate the epidemiology of disease in 2007-2017 children Kawasaki clinical features and risk factors associated with coronary artery lesion investigation.Method:The clinical data of 54 cases of Kawasaki disease in our hospital from January 2007 to July 2017 were retrospectively analyzed.Collate the information collected from the children's questionnaire after admission,according to whether they were complicated with coronary artery disease,they were divided into complications group and non complication group.The clinical characteristics and risk factors of coronary artery disease were analyzed.Result:Among the 54 cases,41 cases(75.93%) were male and 13 cases(24.07%) were female.The main clinical manifestations were fever (92.59%),limb changes(87.04%), rash(72.22%),conjunctival changes(88.89%),lip and oral mucosa changes(90.74%),cervical lymph node enlargement(35.19%) and perianal peeling(38.89%).The complication rate of coronary artery disease was 64.81% (35/54),and the total effective rate was 94.44%(51/54).The gender,white blood cell count,duration of fever and clinical diagnosis between two groups were compared,the differences were not statistically significant(P>0.05),the levels of C-reactive protein,erythrocyte sedimentation rate and platelet in complication group were higher than those of non complication group,and the levels of albumin and age were lower than those of non complication group,the differences were statistically significant(P<0.05).Conclusion:The clinical manifestations of Kawasaki disease have certain characteristics,and the incidence of coronary artery disease is high.The age of children less than 3 years old,the elevated levels of C-reactive protein,platelet and erythrocyte sedimentation rate,and the decreased level of albumin are the influencing factors of coronary artery disease in Kawasaki disease.Monitoring changes in the above indicators will help doctors diagnose and treat Kawasaki disease and improve their prognosis.关键词
川崎病/临床特征/冠状动脉病变Key words
Kawasaki disease/Clinical features/Coronary artery disease引用本文复制引用
林敏仪,林艳,廖惠映,黄斌明..2007-2017年儿童川崎病流行病学临床特征及并发冠状动脉病变危险因素调查分析[J].中国医学创新,2018,15(28):56-59,4.基金项目
佛山市自筹经费类科技计划项目(2017AB003103) （2017AB003103）
