中国医学创新2018，Vol.15Issue(29)：42-45,4.DOI:10.3969/j.issn.1674-4985.2018.29.011
吡格列酮对早期糖尿病肾病患者血清SAA、β-TP及炎症因子水平的影响
Effect of Pioglitazone on Serum of SAA,β-TP and Inflammatory Factors Levels in Patients with Early Diabetic Nephropathy
摘要
Abstract
Objective:To discuss the effect of Pioglitazone on serum of amyloid A(SAA),β-trance protein components(β-TP) and inflammatory factors levels in patients with early diabetic nephropathy. Method:A total of 80 patients with early diabetic nephropathy in our hospitals from January to December 2017 were selected.According to the random number table method,they were divided into experimental group and observation group,40 cases in each group.The control group was given conventional treatment,while experimental group was given Pioglitazone on the basis of this treatment.The levels of serum SAA,β-TP,IL-6,IL-18, TNF-α and hs-CPR before and after treatment between two groups were compared.Result:After treatment,the levels of serum SAA and β-TP in experimental group were lower than those of before treatment and control group, the differences were statistically significant(P<0.05).After treatment,the levels of IL-6,IL-18,TNF-α and hs-CPR in experimental group were lower than those of before treatment and control group,the differences were statistically significant(P<0.05).Conclusion:Pioglitazone can improve the levels of serum SAA,β-TP and inflammatory factors in patients with early diabetic nephropathy,and delay the progression of diabetic nephropathy.关键词
吡格列酮/糖尿病肾病/β痕迹蛋白/淀粉样蛋白A/炎症因子Key words
Pioglitazone/Diabetic nephropathy/β-trance protein components/Amyloid A/Inflammatory factor引用本文复制引用
陈琳,陈文娜,官雯娟..吡格列酮对早期糖尿病肾病患者血清SAA、β-TP及炎症因子水平的影响[J].中国医学创新,2018,15(29):42-45,4.基金项目
江西省卫生计生委科技计划项目(20187347) （20187347）
