中国卒中杂志2018，Vol.13Issue(10)：1029-1034,6.DOI:10.3969/j.issn.1673-5765.2018.10.006
皮层小梗死导致手指功能障碍的预探索研究
Observational Study on Fingers Dysfunction due to Small Cortical Infarction
摘要
Abstract
Objective Simple fingers weakness caused by small cortical infarction is rarely found in clinical practice. This study aimed to investigate the pathogenesis mechanism, clinical presentation and imaging features of such cases. Methods Outpatients with the main manifestation of fingers dysfunction caused by small cortical infarcts from Zhengzhou People's Hospital from July 2009 to December 2016 were included in this study. The analyzed clinical data included sensory and moter functions in fingers, muscle strength of fingers (bending, stretching, adduction and outreach), and the possible pathogenesis mechanism or etiology in medical records. According to the predominant impaired fingers, the patients were divided into ulnar-lateral group and radial-lateral group. The locations of cerebral infarction were identified by diffusion weighted imaging. Based on the imaging, the distance from cerebral falx to lesion core (B) and distance from cerebral falx to the lateral margin of brain (A) were measured and the ration of B/A were calculated. Results A total of 13 cases with small cortex infarction were included, with 6 ones in ulnar-lateral group and 7 ones in radial-lateral group. B/A in ulnar-lateral group was (0.50±0.07), while B/A in radial-lateral group was (0.71±0.06), and the difference between the two groups had statistical significance (t=-5.67, P<0.05). The possible pathogenesis mechanism or etiology in ulnar-lateral group were as follows: large artery stenosis/impaired clearance of emboli in 5 cases and unexplained embolism in 1 case; and that in radial-lateral group were the following: artery-to-artery embolism in 4 cases, cardiogenic embolism in 2 cases, and Moyamoya disease in 1 case. Conclusions The simple impaired finger function is associated with small cortical infarction. The ulnar-lateral finger impairment is associated with medial cortex infarction, which may be associated with hypoperfusion. The radial-lateral finger impairment is associated with lateral cortex infarction, which may be associated with embolism.关键词
皮层小梗死/手指功能障碍/发病机制Key words
Small cortical infarction/Finger dysfunction/Pathogenesis引用本文复制引用
付胜奇,张杰文,杨冬冬,石宝洋,李浩然,张洪涛,张淑玲..皮层小梗死导致手指功能障碍的预探索研究[J].中国卒中杂志,2018,13(10):1029-1034,6.基金项目
郑州市科技攻关项目(20140462) （20140462）
