国际医药卫生导报2018，Vol.24Issue(23)：3539-3541,3.DOI:10.3760/cma.j.issn.1007-1245.2018.23.004
维持性血液透析退出患者铁代谢特点及危险因素分析
Analysis of iron metabolism characteristics and risk factors in patients with maintenance hemodialysis withdrawal
摘要
Abstract
Objective To analyze the pathological characteristics of iron metabolism in patients who have dropped out hemodialysis, and risk factors. Methods A 3-year research was conducted at the kidney disease centre of our hospital to determine the risk factors which affect the life quality of maintenance hemodialysis (MHD) patients. The clinical data such as iron metabolism and biochemical indicators were examined among 169 patients with end-stage renal disease (ESRD). Results Of 169 patients with MHD, 30 cases quitted dialysis due to various adverse outcomes (death, transfer to peritoneal dialysis), and the other 139 cases were still in our centre to receive hemodialysis. The serum ferritin increased in both groups, while the changes of serum total iron-binding capacity (TIBC), blood albumin level, and carbon dioxide binding force were significantly different. The COX regression analysis showed that the TIBC, albumin, and carbon dioxide binding force were the independent factors which influenced the life quality of dialysis patients. Conclusion The detection of iron parameters in MHD patients should be strengthened, the intravenous iron treatment should be carefully conducted, and doctors should correct malnutrition and maintain the electrolyte and acid-base balance clinically for MHD patients, in order to improve their life quality.关键词
终末期肾病/铁代谢/总铁结合力/血液透析/危险因素Key words
End-stage renal disease/Iron metabolism/Total iron-binding capacity/Hemodialysis/Risk factor引用本文复制引用
杨椹,张云芳,田鲁,化宝军,赵世莉,王琦..维持性血液透析退出患者铁代谢特点及危险因素分析[J].国际医药卫生导报,2018,24(23):3539-3541,3.基金项目
广东省自然科学基金(2016A030313420) （2016A030313420）
广东省科技计划项目(粤科规财[2015]110号 0024) （粤科规财[2015]110号 0024）
广州市医学重点学科建设项目(2017-2020) （2017-2020）
广州市花都区科技计划项目(17-HDWS-001)Fund program: Natural Science Foundation of Guangdong Province of China (2016A030313420) （17-HDWS-001）
Science and Technology Planning Project of Guangdong Province ([2015]No.110-0024) （[2015]No.110-0024）
Guangzhou Medical Key Subject Construction Project (2017-2020) （2017-2020）
Science and Technology Planning Project of Huadu District (17-HDWS-001) （17-HDWS-001）
