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Preparation, optimization, and characterization of chitosancoated solid lipid nanoparticles for ocular drug delivery

Fengzhen Wang Mingwan Zhang Dongsheng Zhang Yuan Huang Li Chen Sunmin Jiang Kun Shi Rui Li

生物医学研究杂志（英文版）2018，Vol.32Issue(6)：411-423,13.
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生物医学研究杂志（英文版）2018，Vol.32Issue(6)：411-423,13.

Preparation, optimization, and characterization of chitosancoated solid lipid nanoparticles for ocular drug delivery

Preparation, optimization, and characterization of chitosancoated solid lipid nanoparticles for ocular drug delivery

Fengzhen Wang 1Mingwan Zhang 2Dongsheng Zhang 3Yuan Huang 4Li Chen 5Sunmin Jiang 6Kun Shi 7Rui Li8

作者信息

  • 1. Department of Pharmacy, the Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu 221002, China
  • 2. School of Pharmacy, Nanjing Medical University, Nanjing, Jiangsu 211166, China
  • 3. Department of Pharmacy, Tongde Hospital of Zhejiang Province, Hangzhou, Zhejiang 310000, China
  • 4. Department of Colorectal Surgery, the First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029,China
  • 5. Department of Pharmacy, the Affiliated Wuxi People's Hospital of Nanjing Medical University, Hospital Wuxi, Jiangsu 214023, China
  • 6. Department of Pharmacy, Jiangsu University, the Affiliated Zhenjiang First People's Hospital Zhenjiang, Jiangsu 212002, China
  • 7. Department of Pharmacy, the Affiliated Wuxi Maternity and Child Health Care Hospital of Nanjing Medical University,Wuxi, Jiangsu 214000, China
  • 8. Department of Orthopedichitosan, Xuzhou Central Hospital, Xuzhou, Jiangsu 221009, China
  • 折叠

摘要

关键词

solid lipid nanoparticle/orthogonal design/Box-Behnken design/ophthalmic administration/chitosan

Key words

solid lipid nanoparticle/orthogonal design/Box-Behnken design/ophthalmic administration/chitosan

分类

医药卫生

引用本文复制引用

Fengzhen Wang,Mingwan Zhang,Dongsheng Zhang,Yuan Huang,Li Chen,Sunmin Jiang,Kun Shi,Rui Li..Preparation, optimization, and characterization of chitosancoated solid lipid nanoparticles for ocular drug delivery[J].生物医学研究杂志（英文版）,2018,32(6):411-423,13.

基金项目

This work was supported by grants from the National Natural Science Foundation of China (81100977). （81100977）

生物医学研究杂志（英文版）

OACSCD

1674-8301

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