摘要
Abstract
Objective To investigate the risk factors of post-stroke cognitive impairment (PSCI) in young ischemic stroke patients. Methods Young patients (age 18-45 years) with ischemic stroke in neurology department of Tianjin Huanhu hospital from December 2016 to December 2017 were enrolled consecutively. Demographic information, vascular risk factors, laboratory test results were collected. All of the patients were assessed by Montreal cognitive assessment (MoCA) scale within 14 days from onset. According to the MoCA score, all patients were divided into PSCI (MoCA score <26) group and normal cognitive function group. Multivariate Logistic regression analysis was used to analyze the independent risk factors of young PSCI. Results A total of 165 young patients (mean age 40.02 ± 5.20; 77.6% male) were identified, and 64.8% (n=107) had PSCI within 14 days from onset. Multivariate Logistic regression analysis showed that the lower level of education [odds ratio (OR) 6.752, 95% confidence interval (CI) 1.385-32.906, P=0.018], higher NIHSS score on admission ( OR 1.660, 95% CI 1.372-2.009, P<0.001), previous ischemic stroke ( OR 3.728, 95% CI 1.376-10.104, P=0.010) were independent risk factors of PSCI in young adult stroke patients. Conclusions The prevalence of PSCI in young people is still high, especially those with lower level of education, higher NIHSS score on admission and previous ischemic stroke, should be paid more attention to screen PSCI.关键词
青年卒中/卒中后认知障碍/危险因素Key words
Young stroke/Post-stroke cognitive impairment/Risk factor
