中国卒中杂志2018，Vol.13Issue(11)：1223-1229,7.DOI:10.3969/j.issn.1673-5765.2018.11.019
脑小血管病与步态障碍相关性研究进展
Advance in Gait Disorder in Cerebral Small Vessel Disease
柴湘婷 1王祥翔 1张瑞霞 1马玲丽 1谭兰2
作者信息
- 1. 1266400 青岛 青岛西海岸新区人民医院神经内科
- 2. 青岛市市立医院神经内科
- 折叠
摘要
Abstract
Gait disorder is an important clinical feature of cerebral small vessel disease (CSVD), and can lead to accidental tumble. Imaging features of CSVD include white matter hyperintensities, lacunar infarction, perivascular spaces, cerebral microbleeds, brain atrophy, abnormal cerebral perfusion, and so on. Broken integrality of spinal cord connection with cortex and basal ganglia, visuospatial and execution function dysfunction, together with cognitive impairment or depression in CSVD were all related to gait disorders. White matter hyperintensities in periventricular and deep frontal lobe can lead to motor coordination and cognitive impairment. Lacunar infarction are often found in those with high risk of motor and cognitive impairment. Perivascular spaces, a degree of cerebral microbleeds, brain atrophy and abnormal cerebral perfusion all can bring about gait disorders related to cognitive impairment. Based on clinical and imaging characteristics, this article reviewed the pathogenesis of gait disorders in CSVD.关键词
脑小血管病/步态障碍/跌倒/认知障碍/抑郁Key words
Cerebral small vessel disease/Gait disorder/Tumble/Cognitive impairment/Depression引用本文复制引用
柴湘婷,王祥翔,张瑞霞,马玲丽,谭兰..脑小血管病与步态障碍相关性研究进展[J].中国卒中杂志,2018,13(11):1223-1229,7.
