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Neuroprotective effects of rapamycin on spinal cord injury in rats by increasing autophagy and Akt signaling

Xi-Gong Li Jun-Hua Du Yang Lu Xiang-Jin Lin

中国神经再生研究(英文版)2019,Vol.14Issue(4):721-727,7.
中国神经再生研究(英文版)2019,Vol.14Issue(4):721-727,7.DOI:10.4103/1673-5374.247476

Neuroprotective effects of rapamycin on spinal cord injury in rats by increasing autophagy and Akt signaling

Neuroprotective effects of rapamycin on spinal cord injury in rats by increasing autophagy and Akt signaling

Xi-Gong Li 1Jun-Hua Du 1Yang Lu 1Xiang-Jin Lin1

作者信息

  • 1. Department of Orthopedic Surgery, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang Province, China
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摘要

关键词

nerve regeneration/rapamycin/mammalian target of rapamycin, mTOR/autophagy/Beclin 1/3-methyladenine/acute spinal cord injury/apoptosis/Bax/Akt/neural regeneration

Key words

nerve regeneration/rapamycin/mammalian target of rapamycin, mTOR/autophagy/Beclin 1/3-methyladenine/acute spinal cord injury/apoptosis/Bax/Akt/neural regeneration

引用本文复制引用

Xi-Gong Li,Jun-Hua Du,Yang Lu,Xiang-Jin Lin..Neuroprotective effects of rapamycin on spinal cord injury in rats by increasing autophagy and Akt signaling[J].中国神经再生研究(英文版),2019,14(4):721-727,7.

基金项目

This study was supported by the National Natural Science Foundation of China, No. 81401004 (to XGL) (to XGL)

the Medical and Health Technology Development Program of Zhejiang Province of China, No. 2015-KY1001-036 (to XGL). (to XGL)

中国神经再生研究(英文版)

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1673-5374

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