中国卒中杂志2018，Vol.13Issue(12)：1277-1281,5.DOI:10.3969/j.issn.1673-5765.2018.12.009
溶血磷脂酸在动脉粥样硬化病变中的作用
The Effects of Lysophosphatidic Acid in Atherosclerotic Lesion
摘要
Abstract
Atherosclerosis is a severe and chronic inflammatory arterial disease that can lead to coronary heart disease, ischemic stroke and etc. Lysophosphatidic acid (LPA) plays a crucial role in the progression of atherosclerotic lesion by acting on endothelial cells, vascular smooth muscle cells, monocytes/macrophages, fibroblasts, dendritic cells, T-lymphocytes and platelets, which promotes atherosclerosis and thrombosis. Studies on the effects and pathophysiologic mechanisms of LPA in the atherosclerosis can contribute to find potential drugs and prevention measures for anti-atherosclerosis.关键词
溶血磷脂酸/动脉粥样硬化/血栓形成/内皮细胞Key words
Lysophosphatidic acid/ Atherosclerosis/ Thrombosis/ Endothelial cell引用本文复制引用
张建平,李亚峰,郭庚..溶血磷脂酸在动脉粥样硬化病变中的作用[J].中国卒中杂志,2018,13(12):1277-1281,5.基金项目
国家自然科学基金(81201991)中国博士后科学基金(2015M571068,2016T90115)北京博士后工作经费资助项目(2015ZZ56)山西省高等学校创新人才支持计划(晋教科[2013]8号) （81201991）
