中国现代医生2018,Vol.56Issue(35):37-39,3.
TG、HDL-C、TC与糖尿病周围神经病变的相关性研究
Correlation between TG, HDL-C, TC and diabetic peripheral neuropathy
摘要
Abstract
Objective To explore the correlation between Triglyceride (TG), high density lipoprotein cholesterol (HDL-C), total cholesterol (TC) and diabetic Peripheral neuropathy, and to provide a clinical basis for the diagnosis of diabetic peripheral neuropathy. Methods A total of 48 patients with diabetic peripheral neuropathy diagnosed in our hospital from January 2017 to January 2018 were retrospectively analyzed and enrolled into the DPN group. Another 48 patients with type 2 diabetes admitted to our hospital during the same period were included in the T2DM group. The differences of triglyceride (TG), total cholesterol (TC), high density lipoprotein cholesterol (HDL-C),low density lipoprotein cholesterol (LDL-C),and apolipoprotein B (ApoB) between the two groups were analyzed. And the correlation between these indicators and diabetic peripheral neuropathy were analyzed by logistic regression equation. Results The levels of TG, TC, LDL-C and ApoB in the DPN group were significantly higher than those in the T2DM group, and HDL-C was significantly lower in the DPN group than that in the T2DM group (P<0.05). Logistic regression equation analysis showed that TG, TC, and HDL-C, LDL-C, ApoB were risk factors for the onset of DPN (P<0.05). Conclusion The level of blood lipids in patients with diabetic peripheral neuropathy is higher than that in patients with diabetes alone. The levels of TG, TC and HDL-C,LDL-C, ApoB are closely related to the pathogenesis of DPN, which are important factors leading to neuromicrovascular disease.关键词
甘油三酯(TG)/高密度脂蛋白胆固醇(HDL-C)/总胆固醇(TC)/2型糖尿病/周围神经病变/相关性Key words
Triglyceride (TG)/ High density lipoprotein cholesterol (HDL-C)/ Total cholesterol (TC)/ Type 2 diabetes/ Peripheral neuropathy/ Correlation分类
医药卫生引用本文复制引用
万芳,曹玲玲,孙斐..TG、HDL-C、TC与糖尿病周围神经病变的相关性研究[J].中国现代医生,2018,56(35):37-39,3.基金项目
江西省卫生计生委科技计划项目(20177080) (20177080)