摘要
Abstract
Objective To evaluate the clinical value of ambroxol hydrochloride in the treatment of chronic bronchitis.Methods A total of 80 patients with chronic bronchitis admitted to our hospital from May,2017 to May,2018 were selected,and randomly divided into a treatment group and a control group,40 cases for each group.The control group were conventional treated;in addition,the treatment group were treated with ambroxol hydrochloride.The clinical symptom remission time,symptom score,pulmonary function,changes of inflammatory factor levels,blood gas indexes,total therapeutic efficacy,and incidence of adverse reactions were analyzed in the two groups.Results The times for the remission of cough,expectoration,fever,and lung rales were (2.45±1.27) d,(4.51±2.41) d,(2.16±0.53) d,and (4.61±1.85) d in the treatment group,which were lower than those in the control group,with statistical differences (all P ＜ 0.05).The scores of cough,expectoration,fever,and lung rales were (0.57±0.27),(0.51±0.41),(0.16±0.13),and (0.61±0.35) in the treatment group,which were lower than those in the control group,with statistical differences (all P ＜ 0.05).The levels of inflammatory factors and blood gas indexes were better in the treatment group than in the control group,with statistical differences (all P ＜ 0.05).Adverse reactions,such as pharyngeal discomfort,rapid heart rate,and gastrointestinal reaction,occurred in both groups after treatment,but were effectively relieved after stopping the drug for 2 days,with no statistical difference between these two groups (P ＞ 0.05).Conclusion Ambroxol hydrochloride for chronic bronchitis is effective,with controllable side effects,so it is worth being generalized.关键词
慢性支气管炎/盐酸氨溴索/症状评分/肺功能/炎症因子水平/治疗效果Key words
Chronic bronchitis/Ambroxol hydrochloride/Symptom score/Lung function/Levels of inflammatory factors/Treatment effect
