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风险护理对胃癌患者的预后及血清Cyclin D1因子表达的影响

栾晓娜 邢超然 邵静 王晓庆 朱祥苓

肿瘤药学2018,Vol.8Issue(6):965-968,1000,5.
肿瘤药学2018,Vol.8Issue(6):965-968,1000,5.DOI:10.3969/j.issn.2095-1264.2018.06.29

风险护理对胃癌患者的预后及血清Cyclin D1因子表达的影响

The Effect of Risk Nursing on the Prognosis and the Expression of Cyclin D1 in Serum of Gastric Cancer Patients

栾晓娜 1邢超然 1邵静 1王晓庆 1朱祥苓1

作者信息

  • 1. 青岛大学附属青岛市立医院,山东 青岛,266000
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摘要

Abstract

Objective To explore the effect of risk nursing in assisting treatment of capecitabine combined with hydroxycamptothecin on the expression of Cyclin D1 in patients with gastric cancer. Methods A total of 130 cases of gastric cancer patients in our hospital from January 2017 to January 2018 were selected and divided into the control group (n=65) and the observation group (n=65) randomly. All pa-tients were treated with capecitabine combined with hydroxycamptothecin. And the patients in control group got routine nursing, while those in the observation group were assisted with risk nursing. The general data of the two groups, the occurrence of complications, the changes of the related factors in the serum, the nursing results and the compliance of the nursing care were observed and compared. Results The inci-dence of complications in the observation group was significantly lower than that of the control group (P<0.05). The patients in the observa-tion group achieved better results in nursing and compliance than those in the control group (P<0.05). The serum levels of Cyclin D1 factor, Hcy, IL-10 and hs-CRP of the observation group were significantly higher than those of the control group (P<0.05). Conclusion The risk nursing in assisting treatment of capecitabine and hydroxycamptothecin had good effects for patients with gastric cancer. It helps to reduce the incidence of complications, regulate the serum Cyclin D1 factor and improve the patient's quality of life.

关键词

胃癌/风险护理/卡培他滨/羟基喜树碱/护理满意度/护理依从性

Key words

Gastric cancer/Risk nursing/Capecitabine/Hydroxycamptothecin/Inflammatory factors/Nursing satisfaction/Nursing compliance/Complications

分类

医药卫生

引用本文复制引用

栾晓娜,邢超然,邵静,王晓庆,朱祥苓..风险护理对胃癌患者的预后及血清Cyclin D1因子表达的影响[J].肿瘤药学,2018,8(6):965-968,1000,5.

肿瘤药学

OACSTPCD

2095-1264

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