动物营养学报2019，Vol.31Issue(2)：560-566,7.DOI:10.3969/j.issn.1006-267x.2019.02.010
Wnt信号调控骨骼肌生长、发育与再生的机制
Regulatory Mechanism of Wnt Signaling in Skeletal Muscle Growth, Development and Regeneration
摘要
Abstract
Wnt signaling is a complex network of proteins involved in the regulation of biological processes such as growth, development and regeneration. Skeletal muscle is a kind of dynamic and diversified tissue, which is an essential part of animal body to maintain normal growth and development. As one of the regulatory factors, Wnt signaling regulates the growth, development and regeneration of skeletal muscle mainly by indu-cing the occurrence of skeletal muscle in embryonic stage and activating adult skeletal muscle satellite cells. In recent years, the role and mechanism of Wnt signaling in the growth and development of skeletal muscle have attracted wide attention. Therefore, this review systematically elaborated the role of Wnt signaling in skeletal muscle development, self-renewal and muscle fiber formation, in order to provide theoretical basis for the ani-mal husbandry production and treatment of muscle diseases.[Chinese Journal of Animal Nutrition, 2019, 31 (2) :560-566]关键词
骨骼肌/骨骼肌卫星细胞/Wnt信号/生长发育Key words
skeletal muscle/satellite cells/Wnt signaling/growth and development分类
农业科技引用本文复制引用
张宗明,金成龙,严会超,王修启..Wnt信号调控骨骼肌生长、发育与再生的机制[J].动物营养学报,2019,31(2):560-566,7.基金项目
十三五国家重点研发计划(2018YFD0500403) （2018YFD0500403）
广州市科技计划项目(201704030005) （201704030005）
广东省科技计划项目(2017A050501028,808267680126) （2017A050501028,808267680126）
