动物营养学报2019,Vol.31Issue(2):567-574,8.DOI:10.3969/j.issn.1006-267x.2019.02.011
碱性氨基酸转运载体基因在骨骼肌中的表达规律及其调控
Cationic Amino Acid Transporters Expression Pattern and Regulation in Skeletal Muscle
摘要
Abstract
Skeletal muscle is an important component of the animal body and closely related to the growth, movement and metabolism of living body. Previous studies shown that the increasing in skeletal muscle mass depended on the relative rate of protein synthesis and degradation, and the efficiency of protein synthesis main-ly depended on the dietary composition and content of amino acids. Lysine ( Lys) and other cationic amino acids are essential amino acids for the growth and development of animals, while the cationic amino acid trans-porters ( CATs) are the major transporters for cellular uptake these cationic amino acids, and play an important role in the absorption of basic amino acids such as lysine and arginine. This review focused on the classifica-tion, function, expression regulation as well as the regulation mechanism of CATs, aimed to provide a theoret-ical reference for the high uptake and utilization efficiency of amino acids.[ Chinese Journal of Animal Nutri-tion, 2019, 31(2) :567-574]关键词
骨骼肌/赖氨酸/碱性氨基酸转运载体/蛋白质合成Key words
skeletal muscle/lysine/cationic amino acid transporter/protein synthesis分类
农业科技引用本文复制引用
张凡,严会超,王修启,高春起..碱性氨基酸转运载体基因在骨骼肌中的表达规律及其调控[J].动物营养学报,2019,31(2):567-574,8.基金项目
十三五国家重点研发计划(2018YFD0500403) (2018YFD0500403)
广州市科技计划项目(201704030005) (201704030005)
广东省科技计划项目(2017A050501028) (2017A050501028)