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短链脂肪酸对氧化应激-炎症的影响研究进展

LIN Lixia GAO Chenlin GU Junling HUANG Wei

医学分子生物学杂志2019，Vol.16Issue(1)：93-98,6.

医学分子生物学杂志2019，Vol.16Issue(1)：93-98,6.DOI:10. 3870/j. issn. 1672-8009. 2019. 01. 017

短链脂肪酸对氧化应激-炎症的影响研究进展

Advances in the Effects of Short-chain Fatty Acids on Oxidative Stress and Inflammation

LIN Lixia ¹GAO Chenlin ¹GU Junling ¹HUANG Wei²

作者信息

1. Faculty of Chinese Medicine, Macau University of Science and Technology, Macau, 999078, Chi-na
2. Department of Endocrinology, Affiliated Hospital of Southwest Medical University, Luzhou, Si-chuan, 646000, China
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摘要

Abstract

Short-chain fatty acids ( SCFAs) are mainly metabolites of dietary fiber fermented by intestinal flora. They include acetate, propionate, and butyrate. Recent studies have found that SCFAs play an important role in the prevention and treatment of inflammatory bowel disease, type 2 diabetes and obesity by regulating local and systemic oxidative stress-inflammation signals and the expression and secretion of related cytokines. This article reviews the origin, distribution, mecha-nism of these SCFAs and their effects on oxidative stress-inflammation in order to provide information for clinical and scientific research work.

关键词

短链脂肪酸/氧化应激/炎症

Key words

short-chain fatty acids ( SCFAs) /oxidative stress/inflammation

分类

医药卫生

引用本文复制引用

LIN Lixia,GAO Chenlin,GU Junling,HUANG Wei..短链脂肪酸对氧化应激-炎症的影响研究进展[J].医学分子生物学杂志,2019,16(1):93-98,6.

基金项目

国家自然科学基金(No.81800741) （No.81800741）

医学分子生物学杂志

OACSTPCD

ISSN：1672-8009

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