中国卒中杂志2019，Vol.14Issue(1)：23-28,6.DOI:10.3969/j.issn.1673-5765.2019.01.004
缺血性卒中患者左心室质量指数与颅内、外动脉狭窄的相关性
Correlation between Left Ventricular Mass Index and Extra-and Intracranial Artery Stenosis in Ischemic Stroke Patients
摘要
Abstract
Objective To evaluate the relationship between left ventricular mass index (LVMI) and cervicocerebral atherosclerotic stenosis. Methods Ischemic stroke patients with echocardiography and digital subtraction angiography (DSA) examination from Jinling hospital from January 2017 to October 2017 were enrolled in this study. The subjects were divided into mild and moderate-severe stenosis groups according to the degree of extra- and intracranial atherosclerotic stenosis. LVMI was calculated by the criteria of American Society of Echocardiography (ASE). The traditional risk factors of cerebral atherosclerosis such as age, gender, hypertension, diabetes, coronary artery disease, lipids, and left ventricular mass (LVM) and LVMI, were compared between the mild and moderate-severe stenosis group. Univariate analysis and bivariate regression analysis were performed to analyze the independent risk factors of cervicocerebral atherosclerotic stenosis and the correlation of LVMI and cervicocerebral stenosis degree. Results Among the 169 enrolled patients, 85 (50.3%) with extracranial atherosclerotic stenosis, and 84 (49.7%) with intracranial atherosclerotic stenosis. For patients with extracranial atherosclerotic stenosis, those with moderate-severe stenosis were older than whom with mild stenosis [(64.3±12.4) vs (56.0±13.2) years old, P=0.001], and the LVMI in moderate-severe stenosis group were higher than that in mild stenosis group[(43.6±10.3) vs (36.6±7.2) g/m2.7, P<0.001]. For patients with intracranial atherosclerotic stenosis, LVMI were lower in patients with mild stenosis than that in patients with moderate-severe stenosis [(36.5±7.2) vs (46.1±13.6), P<0.001]. Spearman correlation analysis showed that there was a positive correlation between LVMI and cervicocerebral stenosis rate ( r=0.553, P<0.001). Bivariate logistic regression analysis showed that LVMI ( OR 1.13, 95% CI 1.05-1.21), age ( OR 1.06, 95% CI 1.01-1.11) were independent risk factors of severe extracranial atherosclerotic stenosis. Conclusions LVMI was positively correlated with cervicocerebral atherosclerotic stenosis in patients with ischemic stroke. LVMI was an independent risk factor of severe extracranial atherosclerotic stenosis.关键词
缺血性卒中/左心室质量指数/颅内动脉/颅外动脉/动脉粥样硬化性狭窄Key words
Ischemic stroke/Left ventricular mass index/Extracranial artery/Intracranial artery/Atherosclerotic stenosis引用本文复制引用
赵敏,李顺,王猛猛,徐格林..缺血性卒中患者左心室质量指数与颅内、外动脉狭窄的相关性[J].中国卒中杂志,2019,14(1):23-28,6.基金项目
上海市科委西医引导类项目(16411969900) （16411969900）
