中国卒中杂志2019，Vol.14Issue(1)：43-48,6.DOI:10.3969/j.issn.1673-5765.2019.01.008
基于社区人群的性别与颈动脉粥样硬化斑块内出血关系的研究
Association of Sex and Intra-plaque Hemorrhage in Carotid Artery in Community-Based Population
王宇 1赵锡海 2王拥军 3刘改芬 3张润华 4姜勇 1于淼欣 2洪音 3王畇 1乔会昱 2韩永军 3李东野1
作者信息
- 1. 100070 北京首都医科大学附属北京天坛医院
- 2. 国家神经系统疾病临床医学研究中心
- 3. 首都医科大学北京脑重大疾病研究院
- 4. 清华大学医学院生物医学工程系,生物医学影像研究中心
- 折叠
摘要
Abstract
Objective To investigate the association between sex and intra-plaque hemorrhage (IPH) in carotid artery diagnosed by HR-MRI in a community-based population. Methods A cross-sectional study was conducted in Tsinghua community-based population. Data of demographic information, medical history of hypertension, diabetes and hyperlipidemia, smoking and drinking, physical examinations, laboratory test and other information were collected. According to whether there was IPH in carotid artery by HR-MRI, all subjects were classified as IPH group and no IPH group. Multivariate logistic regression analysis was performed to analyze the association of sex and IPH. Results Of all 246 participants, with 105 (42.7%) were males and a mean age of 64.8 years. There were 12 (4.88%) subjects with IPH. Comparing with the no IPH group, the IPH group had more males (83.3% vs 40.6%, P=0.004), a higher proportion of hypertension (91.7% vs 43.2%, P=0.001) and diabetes mellitus (50.0% vs 12.4%, P<0.001), a higher level of fasting blood glucose [(6.30±1.63) mmol/L vs (5.00±0.99) mmol/L, P<0.001]. The multivariate logistic analysis showed that sex was an independent risk factor of IPH in carotid artery ( OR 7.68, 95% CI 1.10-53.81, P=0.040). Conclusions Male may be an independent risk factor of IPH in carotid artery.关键词
性别/颈动脉/动脉粥样硬化/斑块内出血/危险因素Key words
Sex/Carotid artery/Atherosclerotic plaque/Intra-plaque hemorrhage/Risk factor引用本文复制引用
王宇,赵锡海,王拥军,刘改芬,张润华,姜勇,于淼欣,洪音,王畇,乔会昱,韩永军,李东野..基于社区人群的性别与颈动脉粥样硬化斑块内出血关系的研究[J].中国卒中杂志,2019,14(1):43-48,6.
