烟草科技2019，Vol.52Issue(1)：37-44,8.
两种抽吸模式下不同圆周卷烟主流烟气释放物及毒理学分析
Analysis of emission and in vitro toxicology of mainstream smoke of cigarettes with different circumferences under ISO and HCI smoking regimes
摘要
Abstract
To investigate the emission and toxicology characteristics in mainstream smoke of cigarettes with different circumferences,the routine smoke indexes,the priority toxicant H index and in vitro toxicology of mainstream smoke of research cigarettes with three different circumferences of the same tobacco blend were analyzed under ISO and Health Canada Intensive (HCI) smoking regimes. The puff-by-puff release characteristics of routine smoke indexes of mainstream cigarette smoke were studied as well. The results showed that:1) Under ISO smoking regime,the mainstream smoke release from the cigarette with medium circumference had the lowest routine smoke indexes and H index per unit nicotine yield. Under HCI smoking regime,with the decrease of cigarette circumference,the H index per unit nicotine yield decreased. 2)Under the different smoking regimes,with the decrease of cigarette circumference,the in vitro cytotoxicity of total particulate matters decreased generally,however no obvious difference was observed in genotoxicity and mutagenicity. 3)For the cigarettes with the different circumferences,the puff-by-puff releases of routine smoke indexes of mainstream cigarette smoke generally increased with the puff number.关键词
卷烟/圆周/抽吸模式/主流烟气/释放物/毒理学/逐口释放量Key words
Cigarette/Circumference/Smoking regime/Mainstream cigarette smoke/Emission/Toxicology/Puff-by-puff release分类
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..两种抽吸模式下不同圆周卷烟主流烟气释放物及毒理学分析[J].烟草科技,2019,52(1):37-44,8.基金项目
国家烟草质量监督检验中心科技创新项目"烟用纸张中偶氮染料的测定方法研究"(562015CA0090). （562015CA0090）
