中国卒中杂志Issue(2)：116-120,5.DOI:10.3969/j.issn.1673-5765.2019.02.006
卒中后失语患者非语言认知功能损害特点的临床研究
Clinical Study of Non-linguistic Cognitive Impairment in Patients with Post-Stroke Aphasia
摘要
Abstract
Objective To explore the characteristics of non-linguistic cognitive impairment in patients with post-stroke aphasia, and to analyze the relationship between language impairment and non-linguistic cognitive impairment in patients with aphasia after stroke. Methods Thirty-two patients with stroke in Beijing Tian Tan Hospital were selected. The language function of all the patients during hospitalization were assessed by Western Aphasia Battery (WAB), and they were divided into aphasia group (n=15) and non-aphasia group (n=17). The non-linguistic cognitive function were assessed by the second edition of the Chinese version of Loewenstein Occupational Therapy Cognitive Assessment (LOTCA) battery. The sub-item and total scores of LOTCA in the two groups were compared, and the sub-item scores of WAB and the sub-item and total scores of LOTCA were analyzed by partial correlation analysis. Parallel multiple stepwise regression analysis was conducted to identify the factors influencing aphasic quotient. Results The total score of LOTCA in aphasia group was signiflcantly lower than that in non-aphasia group [85.0 (69.0-92.0) vs 99.0 (86.0-102.5), P<0.05]. The total score of LOTCA were positively correlated with WAB sub-item scores and aphasia quotient (r=0.587-0.883, P<0.05), the sub-item scores of LOTCA were positively correlated with WAB sub-item scores (r=0.521-0.843, P<0.05), and multiple stepwise regression analysis showed that the main factor affecting aphasia quotient was the total score of LOTCA (β=0.707, P=0.003). Conclusions There is non-linguistic cognitive impairment in patients with aphasia after stroke. The more severe aphasia, the more severe non-linguistic cognitive impairment.关键词
卒中/失语症/认知功能障碍Key words
Stroke/Aphasia/Cognitive impairment引用本文复制引用
刘鑫鑫,马艳玲,刘艳君,姚婧璠,张玉梅..卒中后失语患者非语言认知功能损害特点的临床研究[J].中国卒中杂志,2019,(2):116-120,5.基金项目
国家重点研发项目"老年常见神经系统疾病综合康复体系研究"分课题"老年全周期康复技术体系与信息化管理研究"(SQ2018YFC200065-02)北京市医管局"扬帆计划"重点医学扶持项目(ZYLX201836)国家自然科学基金面上项目(8137120) （SQ2018YFC200065-02）
