动物营养学报2019，Vol.31Issue(4)：1554-1563,10.DOI:10.3969／j.issn.1006⁃267x.2019.04.012
植物多酚对氧化应激与炎症信号通路的调控机制
Regulation Mechanism of Plant Polyphenols in Oxidative Stress and Inflammatory Signaling Pathways
摘要
Abstract
Inflammation and oxidative stress are main causes of tissue and organ damage in animals. The intes﹣tinal inflammation may cause damage to intestinal mucosa, and thereby affecting its barrier function and weake﹣ning the animal’s ability to defend against external stimuli. Plant polyphenols are characterized by low toxicity and no drug resistance, and possess multiple potential biological effects such as antioxidant, anti﹣inflammation and intestinal flora regulation. Therefore, polyphenols have a wide application prospect in the development of novel feed additives. However, polyphenols have not been used rationally since the metabolic and regulatory mechanisms of most plant polyphenols are still not clear. Based on recent studies, this paper has summarized the regulation of oxidative stress and inflammatory signaling pathways by plant polyphenols to provide a theo﹣retical basis for their application in novel feed additives.[ Chinese Journal of Animal Nutrition, 2019, 31(4) :1554?1563]关键词
多酚/氧化应激/炎症/调控机制Key words
polyphenols/ oxidative stress/ inflammation/ regulatory mechanism分类
农业科技引用本文复制引用
贺宇佳,刘明,伍树松..植物多酚对氧化应激与炎症信号通路的调控机制[J].动物营养学报,2019,31(4):1554-1563,10.基金项目
国家自然科学基金应急管理项目(31741115) （31741115）
动物营养学国家重点实验室开放课题(2004DA125184F1724) （2004DA125184F1724）
湖南省百人计划(2017) （2017）
