中国免疫学杂志2019,Vol.35Issue(2):236-239,4.DOI:10.3969/j.issn.1000-484X.2019.02.022
骨肉瘤免疫靶向治疗相关机制的研究进展
Advances in research on related mechanisms of immune-targeted therapy on osteosarcoma
摘要
Abstract
Osteosarcoma, originated from mesenchymal tissue, is one of the highest incidence of primary malignant bone tumors which were characteristic double peak distribution both in adolescents and elderly. Immune-targeted therapy could block the tumor cell signaling pathway and promote cancer cell death by apoptosis. Immune-targeted therapy is an effective treatment of anti-osteosarcoma after surgery and chemotherapy in recent years. The paper reviews the advances in latest research on the related mechanisms of the immune-targeted therapy on osteosarcoma, and hope to provide a theoretical basis for clinical treatment.关键词
骨肉瘤/靶向治疗/免疫治疗/信号通路Key words
Osteosarcoma/Targeted therapy/Immunotherapy/Signaling pathway分类
医药卫生引用本文复制引用
曾新歆,王胜涛,贵鹏,吴昊,李朝旭..骨肉瘤免疫靶向治疗相关机制的研究进展[J].中国免疫学杂志,2019,35(2):236-239,4.基金项目
国家自然科学基金 (81360400) 资助项目 (81360400)