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骨肉瘤免疫靶向治疗相关机制的研究进展

曾新歆 王胜涛 贵鹏 吴昊 李朝旭

中国免疫学杂志2019,Vol.35Issue(2):236-239,4.
中国免疫学杂志2019,Vol.35Issue(2):236-239,4.DOI:10.3969/j.issn.1000-484X.2019.02.022

骨肉瘤免疫靶向治疗相关机制的研究进展

Advances in research on related mechanisms of immune-targeted therapy on osteosarcoma

曾新歆 1王胜涛 1贵鹏 1吴昊 1李朝旭2

作者信息

  • 1. 桂林医学院附属医院骨二科, 桂林 541004
  • 2. 桂林医学院附属南溪山医院(广西壮族自治区南溪山医院)创伤手外科, 桂林 541002
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摘要

Abstract

Osteosarcoma, originated from mesenchymal tissue, is one of the highest incidence of primary malignant bone tumors which were characteristic double peak distribution both in adolescents and elderly. Immune-targeted therapy could block the tumor cell signaling pathway and promote cancer cell death by apoptosis. Immune-targeted therapy is an effective treatment of anti-osteosarcoma after surgery and chemotherapy in recent years. The paper reviews the advances in latest research on the related mechanisms of the immune-targeted therapy on osteosarcoma, and hope to provide a theoretical basis for clinical treatment.

关键词

骨肉瘤/靶向治疗/免疫治疗/信号通路

Key words

Osteosarcoma/Targeted therapy/Immunotherapy/Signaling pathway

分类

医药卫生

引用本文复制引用

曾新歆,王胜涛,贵鹏,吴昊,李朝旭..骨肉瘤免疫靶向治疗相关机制的研究进展[J].中国免疫学杂志,2019,35(2):236-239,4.

基金项目

国家自然科学基金 (81360400) 资助项目 (81360400)

中国免疫学杂志

OA北大核心CSCDCSTPCD

1000-484X

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