国际医药卫生导报2019,Vol.25Issue(8):1196-1199,4.DOI:10.3760/cma.j.issn.1007-1245.2019.08.006
呼吸机相关性肺炎患者呼出气冷凝液中pH及亚硝酸盐检测的临床意义
Clinical significance of pH and nitrite detection in exhaled breath condensate in patients with ventilator-associated pneumonia
摘要
Abstract
Objective To explore the significance of pH and nitrite detection in exhaled breath condensate of patients with ventilator-associated pneumonia.Methods The study was conducted between June 2012 and December 2017.40 patients with gastroesophageal reflux disease and ventilator-associated pneumonia were selected as the observation group,and 40 patients with gastroesophageal reflux disease without ventilator-associated pneumonia were selected as the control group.The pH and nitrite detection of exhaled breath condensate were performed in both groups.The detection results were observed and compared between the two groups.Results In patients with ventilator-associated pneumonia,NO2-increased in exhaled breath condensate,pH decreased,with statistically significant differences compared with patients without ventilator-associated pneumonia (P<0.05).Conclusion The detection of pH and nitrite in exhaled breath condensate can reflect the patients' body state to some extent,and distinguish patients with ventilator-associated pneumonia from patients without pneumonia,providing guidance for clinically accurate treatment.关键词
呼出气冷凝液/pH/亚硝酸盐/呼吸机相关性肺炎/检测意义Key words
Exhaled breath condensate/pH/Nitrite/Ventilator-associated pneumonia/Detection significance引用本文复制引用
涂力,翁恒,陈力舟,张宏英,王新航,黄进宝,潘建光,李红艳..呼吸机相关性肺炎患者呼出气冷凝液中pH及亚硝酸盐检测的临床意义[J].国际医药卫生导报,2019,25(8):1196-1199,4.基金项目
福建省卫生厅青年科研课题(2010-2-74)Youth Research Project of Fujian Provincial Health Department (2010-2-74) (2010-2-74)