摘要
Abstract
Objective To investigate the clinical effect of rt-PA intravenous thrombolysis and superselective arterial thrombolysis in the treatment of acute middle cerebral artery cerebral infarction.Methods The clinical data of 240 patients with acute middle cerebral artery cerebral infarction admitted to Gongyi People's Hospital from January 2015 to Februay 2018 were analyzed.According to the treatment, 210 patients with rt-PA intravenous thrombolysis and 30 patients with superselective arterial thrombolysis.The NIHSS score, fibrinogen (FIB), prothrombin time (PT) and thrombin time (TT) were observed at different time points in the two groups.The revascularization rate and total effective rate of the two groups were compared.Results There were no significant differences in NIHSS scores, FIB, PT and TT between the two groups before thrombolysis (P＞0.05).The super-selective arterial thrombolysis group was treated with TSH for 6 h, 3 d, 7 d, NIHSS score, PT, TT was lower than rt-PA intravenous thrombolysis group, FIB was higher than rt-PA intravenous thrombolysis group, and the recanalization rate and total effective rate of superselective arterial thrombolysis group were higher than that of rt-PA intravenous thrombolysis group.The difference was statistically significant (P＜0.05).Conclusion Superselective arterial thrombolysis is effective in the treatment of acute middle cerebral artery cerebral infarction.The neurological function and coagulation function are improved, and the recanalization rate and total effective rate are high.关键词
急性大脑中动脉脑梗死/缺血性脑血管病/rt-PA/静脉溶栓/超选择性动脉溶栓/颈内动脉Key words
Acute middle cerebral artery cerebral infarction/Ischemic cerebrovascular disease/rt-PA/Intravenous thrombolysis/Superselective arterial thrombolysis/Internal carotid artery分类
医药卫生
