中国医科大学学报2019，Vol.48Issue(3)：240-244,5.DOI:10.12007/j.issn.0258-4646.2019.03.010
肝移植术中入肝血流量对术后早期移植物功能不全的临床意义
Clinical Significance of Intraoperative Blood Flow into the Transplanted Liver in Early Allograft Dysfunction after Liver Transplantation
摘要
Abstract
Objective To determine the risk factors associated with early allograft dysfunction (EAD) after liver transplantation. Methods We retrospectively analyzed the records of 138 patients who underwent liver transplantation from January 2006 to October 2016 in our department. Transplant recipients were divided into two groups:those who met the diagnostic criteria of EAD (EAD group) and those who did not (non-EAD group). We compared blood flow into the transplanted livers and other clinical features between the two groups using univariate and multivariate analysis. Results Intraoperative portal vein flow (PVF) maximum was significantly different between the two groups. Multivariate analysis revealed that intraoperative PVF maximum ＜1 600 mL/min was the only independent risk factor for the occurrence of EAD after liver transplantation in this cohort. Conclusion Intraoperative PVF maximum ＜1 600 mL/min is an independent risk factor for the occurrence of EAD after liver transplantation. Measuring intraoperative blood flow into the transplanted liver in liver transplant recipients may help identify patients at risk for developing EAD.关键词
肝移植/门静脉血流量/早期移植物功能不全/危险因素Key words
liver transplantation/portal vein flow/early allograft dysfunction/risk factor分类
医药卫生引用本文复制引用
郭瑞,李晓航,李峰,刘青鹏,逯宪良,王博文,孟一曼,杨蕾,张佳林..肝移植术中入肝血流量对术后早期移植物功能不全的临床意义[J].中国医科大学学报,2019,48(3):240-244,5.基金项目
辽宁省重点研发计划指导计划(2017225031) （2017225031）
