安徽农业科学2019，Vol.47Issue(2)：10-14,5.DOI:10.3969/j.issn.0517-6611.2019.02.004
细胞自噬与疾病的研究进展
Research Progress of the Autophagy and Disease
摘要
Abstract
Autophagy is a biological process in which cells transport the damaged organelles, waste cytoplasm and denatured or senescent proteins to lysosome, and then undergo enzymatic hydrolysis. Autophagy is a highly conserved process in eukaryotes, and autophagy is a cell self-protective mechanism which maintains the intracellular homeostasis. Autophagy plays an important role in the programmed cell death (PCD), cancer, cardiovascular disease, liver disease, neurodegenic diseases, cancer and tumor, autoimmune diseases and other disases. It was suggested that the autophagy played an important role in the process of immuno related diseases, thus clarifying that cell autophagy may be a new target and breakthrough in the treatment of immune related disease, and pave the way for the treatment of immune related diseases.关键词
细胞自噬/溶酶体/真核生物/疾病Key words
Autophagy/Lysosome/Eukaryotes/Disease分类
生物科学引用本文复制引用
焦寒伟,王红均,赵宇,伍莉,帅学宏,陈吉轩,甘玲,罗献梅,黄庆洲..细胞自噬与疾病的研究进展[J].安徽农业科学,2019,47(2):10-14,5.基金项目
国家自然科学基金项目(31802215) （31802215）
重庆市自然科学基金项目(cstc2018jcyjA0807) （cstc2018jcyjA0807）
西南大学科研基金资助项目(20700505) （20700505）
