安徽医科大学学报2019，Vol.54Issue(2)：296-299,4.DOI:10.19405/j.cnki.issn1000-1492.2019.02.027
手术后肺栓塞的临床特征及危险因素分析
Analysis of clinical features and risk factors of postoperative pulmonary embolism
摘要
Abstract
Objective To analyze the clinical characteristics and risk factors of postoperative acute pulmonary embolism (PE). Methods The clinical data were reviewed for 77 patients with highly suspected PE. Patients were divided into case group (positive results of PE on CTPA) and control group (negative results of PE on CTPA). Clinical characteristics of case group were retrospectively analyzed,and the risk factors of PE in both group were assessed using multivariate logistic regression. Results 22 PE(47. 83％)developed after orthopaedic surgery or general surgery within 1 week after surgery. The most common symptoms were chest distresss or dyspnea (43. 48％). The most common signs were asymmetrical edema of lower limbs (63. 04％). The PE patients involved lower right pulmonary artery more often than other artery blood vessels (58. 70％). Pulmonary embolism was significantly correlated with Well' score≥2 and simplifiedrevised Geneva'score≥3 in univariate analysis. Multiariable Logistic regression showed that men (OR = 5. 300,P = 0. 011),fracture (OR = 14. 383,P = 0. 003),malignant tumor (OR = 10. 381,P = 0. 013),chronic lung disease (OR = 27. 080,P = 0. 006),and immobilize (OR = 5. 518,P = 0. 031) were independent risk factors for the occurrence of pulmonary embolism. Conclusion Postoperative clinical manifestations in patients with PE can be subtle or atypical. Male,fracture,malignant tumor,chronic lung disease, immobilize are independent risk factors for postoperative PE. Combined with clinical prediction score can play an important role for early postoperative timely diagnosis of PE.关键词
肺栓塞/临床特征/危险因素Key words
pulmonary embolism/clinical characteristic/risk factors分类
医药卫生引用本文复制引用
刘云峰,赵卉,张毅,苑仁祥..手术后肺栓塞的临床特征及危险因素分析[J].安徽医科大学学报,2019,54(2):296-299,4.基金项目
国家自然科学基金(编号:81670060) （编号:81670060）
