北京中医药大学学报2019，Vol.42Issue(1)：8-11,4.DOI:10.3969/j.issn.1006-2157.2019.01.002
糖尿病肾病"精损络痹"病机探讨
Pathogenesis of diabetic nephropathy with essence depletion and collateral impediment
摘要
Abstract
The pathogenesis of essence depletion and collateral impediment can summarize the characteristics of core pathogenesis of diabetic nephropathy (DN) and guide clinical treatment effectively.The pathogenesis of essence depletion emphasizes that kidney lesions is the core of five viscera lesions.Kidney deficiency indicates the consumption of kidney essence and deficiency induces the production of stagnation, dampness, stasis and turbidity.The pathogenesis of collateral impediment indicates that dampness, stasis and turbidity due to deficiency obstruct kidney collateral, even aggregation-accumulation is produced.Therefore collateral impediment is characterized by excess due to deficiency.The therapy of filling essence and freeing collaterals is proposed for DN treatment in the paper.The filling essence refers to nourishing kidney essence, and freeing collaterals refers to eliminating pathogens to free collaterals.It is a kernel therapy for DN.The nourishing kidney essence is a cornerstone in DN treatment, especially in middle or late stages of DN treatment.In early stage eliminating pathogens to resolve impediment (eliminating-freeing therapy) is stressed, and in late stage reinforcing healthy qi and eliminating pathogens (nourishing-freeing therapy) is emphasized.The healthy qi will not be damaged during eliminating pathogens.关键词
糖尿病肾病/核心病机/精损/络痹/肾精Key words
diabetic nephropathy/core pathogenesis/essence depletion/collateral impediment/kidney essence分类
医药卫生引用本文复制引用
胡济源,柳红芳,张向伟..糖尿病肾病"精损络痹"病机探讨[J].北京中医药大学学报,2019,42(1):8-11,4.基金项目
国家自然科学基金资助项目(No.81774273) （No.81774273）
北京市科学技术委员会十病十药研发项目(No.Z161100001816003) （No.Z161100001816003）
