吉林大学学报（医学版）2019，Vol.45Issue(1)：170-174,后插4,6.DOI:10.13481/j.1671-587x.20190132
肝脏渡越时间在门静脉高压-食管胃底静脉曲张患者门静脉压力评估中的应用
Application of hepatic transit time in portal vein pressure assessment in patients with portal hypertension and esophago gastric varices
摘要
Abstract
Objective:To analyze the relationship of hepatic transit time and portal vein pressure in the patients with portal hypertension and esophagogastric varices, and to clarify its clinical significance.Methods:A total of50hospitalized patients underwent esophagogastric venous embolization due to portal hypertension and esophagogastric varices were selected as observation group, and 50patients without history of liver disease and clinical manifestations of liver disease (hospitalized or out-patient) were selected as control group, All patients underwent liver contrast enhanced ultrasound.The free portal pressure (FPP) was measured by ultrasound guided portal vein puncture for operating pathways in the patients in observation group.The hepatic artery-hepatic vein transit time (HA-HVTT) , the hepatic portal vein-hepatic vein transit time (PV-HVTT) , the liver parenchymahepatic vein transit time (PA-HVTT) of the patients were compared between two groups.The correlations between HA-HVTT, PV-HVTT, PA-HVTT and FPP of the patients in observation group were analyzed.Results:The HA-HVTT, PV-HVTT and PA-HVTT of the patients in observation group were significantly shorter than those in control group (t=5.078, P＜0.01;t=12.163, P＜0.01;t=2.649, P＜0.01) .The HA-HVTT, PV-HVTT and PA-HVTT had negative correlations with FPP in observation group (r=-0.799, P＜0.01;r=-0.554, P＜0.01;r=-0.735, P＜0.01) .The linear relationship between HA-HVTT and FPP was Y=-0.410X+7.254;the linear relationship between PV-HVTT and FPP was Y=-0.355X+4.983;the linear relationship between PA-HVTT and FPP was Y=-0.566X+4.997.Conclusion:Liver transit time can be used as an effective index to judge the portal vein pressure, and it can provide the theroretical basis for the diagnosis and treatment of portal hypertension in the patients.关键词
肝硬化/食管胃底静脉曲张/超声造影/渡越时间/门静脉压力Key words
cirrhosis/esophagogastric varices/contrast enhanced ultrasound/transit time/portal pressure分类
医药卫生引用本文复制引用
林元强,姜博,李鹤群,金春香,王辉..肝脏渡越时间在门静脉高压-食管胃底静脉曲张患者门静脉压力评估中的应用[J].吉林大学学报（医学版）,2019,45(1):170-174,后插4,6.基金项目
吉林省财政厅吉林省直卫生专项项目资助课题(SCZSY201618) （SCZSY201618）
吉林省科技厅科技发展计划项目资助课题(20170414042G H) （20170414042G H）
