磁共振成像2019，Vol.10Issue(1)：8-13,6.DOI:10.12015/issn.1674-8034.2019.01.002
DWI联合最小ADC值对鉴别诊断颅内孤立性纤维性肿瘤/血管外皮细胞瘤与脑膜瘤的价值
The value of DWI combined with minimum ADC value in differential diagnosis of intracranial solitary fibrous tumor/hemangiopericytoma and meningioma
摘要
Abstract
Objective: Differential diagnosis of intracranial solitary fibrous tumor/hemangiopericytoma (SFT/HPC) and meningioma by diffusion weighted imaging (DWI) combined with minimum apparent diffusion coefficient (MinADC) to improve preoperative diagnostic accuracy. Materials and Methods: Retrospective analysis of preoperative clinical data, DWI characteristics and pathological data of 10 patients with SFT/HPC (WHO Ⅱ grade) and 22 patients with meningioma (WHO Ⅱ grade) confirmed by surgery and pathology from March 2012 to August 2018. MinADC value of the SFT/HPCs (n=10) was measured on ADC map and was compared with that of meningiomas (n=22). Comparison of MinADC values between SFT/HPC and meningioma was conducted by Welch test. Using the receiver operating characteristic curve (ROC curve) to evaluate the differential diagnosis value of MinADC value. Results: In 10 cases of SFT/HPC, the solid components of the tumor showed equal signal (n=8) and slightly higher signal (n=2) on DWI, the mean value of MinADC was (1.16±0.23)×10-3 mm2/s. In 22 cases of meningioma, the solid components of the tumor showed slightly higher signal (n=18) and equal signal (n=2) and high signal (n=2) on DWI, the mean value of MinADC was (0.80±0.12)×10-3 mm2/s, less than that of SFT/HPC, the difference of MinADC values between the two groups was statistically significant (P＜0.01). For the differentiation between SFT/HPC and meningioma, the critical cutoff MinADC value was 0.90×10-3 mm2/s, which provided the best combination of sensitivity (97.6％) and specificity (94.3％), the area under the ROC curve was 0.92±0.32, corresponding to histopathological findings, the Kappa value of the repeat measurements was 0.91 for SFT/HPC and 0.87 for meningioma, which indicated a good concordance of the results. Conclusions: MinADC value can be used as a quantitative tool to distinguish intracranial SFT/ HPC from meningioma and improve the accuracy of preoperative diagnosis.关键词
脑肿瘤/孤立性纤维瘤/血管外皮细胞瘤/磁共振成像Key words
brain neoplasms/solitary fibrous tumors/hemangiopericytoma/magnetic resonance imaging分类
医药卫生引用本文复制引用
梁小红,周青,赵志勇,柯晓艾,韩蕾,周俊林..DWI联合最小ADC值对鉴别诊断颅内孤立性纤维性肿瘤/血管外皮细胞瘤与脑膜瘤的价值[J].磁共振成像,2019,10(1):8-13,6.基金项目
甘肃省卫生行业科研计划项目(编号:GSWSKY2016-06) （编号:GSWSKY2016-06）
兰州大学第二医院博士科研基金(编号:2015-1-04) （编号:2015-1-04）
