磁共振成像2019，Vol.10Issue(2)：121-125,5.DOI:10.12015/issn.1674-8034.2019.02.009
基于多中心新生儿头颅MRI研究分娩方式对颅内出血发病风险的影响
Exploring the influence of delivery mode on the risk of intracranial hemorrhage based on multicenter neonatal brain MRI
摘要
Abstract
Objective: To analyze the influence of different delivery methods on the risk of intracranial hemorrhage (ICH) in neonates based on MRI. Materials and Methods: Retrospectively collected 3464 neonates with head MRI within 14 days after the birth of six hospitals (form Jan 2011 to Oct 2016). Cases with incomplete clinical data, inherited metabolic diseases, congenital craniocerebral dysplasia, prenatal intracranial hemorrhage, and MRI images that could not be used for analysis were excluded. Logistic regression analysis was used to compare the risk of neonatal ICH exposure to different modes of delivery. Results: A total of 1976 neonates were included for analysis. The Logistic regression model corrected for confounding factors and found that the risk of neonatal ICH in vaginal delivery increased by 4.27 times compared with cesarean section. Further stratification of vaginal delivery revealed that neonatal delivered by forceps had the highest risk of ICH, which was 7.52 times higher than those delivered by cesarean section. Among them, forceps delivery significantly increased the risk of subependymal-intraventricular hemorrhage, subarachnoid hemorrhage and subdural hemorrhage in neonates. Conclusions: Vaginal delivery may increase the risk of developing neonatal ICH, especially in forceps.关键词
磁共振成像/分娩方式/新生儿/颅内出血Key words
magnetic resonance imaging/mode of delivery/neonatal/intracranial hemorrhage分类
医药卫生引用本文复制引用
王霞,张增俊,郭玉林,周和平,任转勤,曾令霞,杨健,刘婷,刘哲,孙亲利,蒋昊翔,陈志强,梁煜坤,张雷,姚晓群..基于多中心新生儿头颅MRI研究分娩方式对颅内出血发病风险的影响[J].磁共振成像,2019,10(2):121-125,5.基金项目
国家重点研发计划项目(编号:2016YFC0100300) （编号:2016YFC0100300）
国家自然科学基金面上项目(编号:81471631,81771810,51706178) （编号:81471631,81771810,51706178）
教育部"新世纪优秀人才支持计划"项目(编号:NCET-11-0438) （编号:NCET-11-0438）
中央高校基本科研业务费(编号:xjj2018jchz07) （编号:xjj2018jchz07）
陕西省自然科学基础研究计划(编号:2017JQ8034) （编号:2017JQ8034）
西安交通大学第一附属医院临床研究课题重点项目(编号:XJTU1AF-CRF-2015-004) （编号:XJTU1AF-CRF-2015-004）
西安交通大学第一附属医院科研发展基金(编号:YK201509) （编号:YK201509）
