中国耳鼻咽喉头颈外科2019，Vol.26Issue(1)：21-24,4.DOI:10.16066/j.1672-7002.2019.01.006
高原地区慢性化脓性中耳炎及中耳胆脂瘤的病原菌及药敏分析
Pathogenic bacteria and drug sensitivity analysis of chronic suppurative otitis media and cholesteatoma in plateau area
摘要
Abstract
OBJECTIVE To invest igate the distribution of pathogenic bacteria and the antibiotic susceptibility of otitis media in plateau areaandto guide clinical drug application rationally. METHODS Middle ear secretions were collected from 218 inpatients and outpatients(220 ears) with otitis media in our department from December 2016 to January 2018 and were performed by isolation and identification of pathogenic bacteriaand drug sensitivity test. RESULTS 1. 152 strains of microbes were isolatedincluding 125 casesof bacterial infection and 8 cases of fungal infection. 2. The gram-positive bacteria in middle ear effusions of chronic suppurative otitis media was higher than those of cholesteatoma, of which Staphylococcus aureuswas the most frequently isolated pathogen. While Pseudomonas aeruginosa was the highest in cholesteatoma. 3. The antibiotic sensitivity of pathogenic bacteria varies from strain to strain. CONCLUSION Staphylococcus aureusand Pseudomonas aeruginosa were the main pathogenic bacteria. Common pathogenic bacteria were resistance to penicillin and levofloxacin, which were commonly used in clinic. Therefore, bacterial culture should be carried out and rational drug use should be guided.关键词
中耳炎,化脓性/胆脂瘤,中耳/集落计数,微生物/微生物敏感性试验Key words
Otitis Media, Suppurative/Cholesteatoma, Middle Ear/Colony Count, Microbial/Microbial Sensitivity Tests引用本文复制引用
吕芸,何健,卫旭东,张邵婕,姚玉荣..高原地区慢性化脓性中耳炎及中耳胆脂瘤的病原菌及药敏分析[J].中国耳鼻咽喉头颈外科,2019,26(1):21-24,4.基金项目
甘肃省中医药管理局科研课题项目(GZK-2018-43)和甘肃省卫生行业科研计划项目(GSWSKY2017-29)联合资助 （GZK-2018-43）
