中国耳鼻咽喉头颈外科2019，Vol.26Issue(1)：34-36,3.DOI:10.16066/j.1672-7002.2019.01.009
P1成分对人工耳蜗术后儿童听觉的研究价值及观测指标的选择
Value and assessment of P1 component in children with CIs
摘要
Abstract
OBJECTIVE Aim to explore the value and the selection of observation target of P1 component in children with cochlear implant(CI). METHODS 13 children(4.37±0.73 years old) with right side CI and one year of regular post-CI rehabilitation were recruited as CI group. 15 gender and age (4.25±0.84)years matched children with left side external and middle ear malformation were selected as control group. We collected their AEP which showed their reaction to 1000 Hz pure tone and analyzed the P1 component. RESULTS The cut off value between CI group and control groupwas 10.4mV for P1 Amplitude(P1A) and 110.5 mV for P1 Latency(P1L). More precisely, the values of CI group were above the cut off value while the values of control group were below it. Whether choosing P1A or P1L as dividing standard, the AUC were between 0.5 and 0.9(AUC: P1A0.733, P1L0.800), which showed medium distinguishing significance. P1L component showed greater You-den index(0.590>0.471) and sensitivity(0.923> 0.538) while P1A showed greater specificity(0.933>0.667). CONCLUSION P1L shows greater ability in distinguishing the difference between CI group and control group while P1A has advantage in determining their common feature. Generally, P1L shows higher value in studying CI children. We need to make choice between P1A and P1L in different situation and use P1A and P1L standard in series or parallel.关键词
儿童/诱发电位, 听觉/耳蜗植入术/P1波Key words
Child/Evoked Potentials, Auditory/Cochlear Implantation/P1 component引用本文复制引用
王俊博,梁茂金,刘佳浩,陈越勃,郑亿庆..P1成分对人工耳蜗术后儿童听觉的研究价值及观测指标的选择[J].中国耳鼻咽喉头颈外科,2019,26(1):34-36,3.基金项目
广东省自然科学基金-纵向协同博士科研启动项目(2018A030310117,18zxxt54)和国家自然科学基金资助项目(81800922)联合资助 （2018A030310117,18zxxt54）
