广东医学2019，Vol.40Issue(5)：671-675,5.DOI:10.13820/j.cnki.gdyx.20183930
高血压病患者血压达标与自主神经功能的关系
Association between blood pressure control and autonomic nervous function in hypertensive patients
摘要
Abstract
Objective To investigate the effect of blood pressure (BP) control on cardiac autonomic nervous function by researching the correlation between BP control and heart rate recovery (HRR) and heart rate variability (HRV) in hypertensive patients.Methods Hypertensive patients, who were hospitalized in the department of cardiology during October 2016 to September 2017, were grouped into controlled BP group (n=71) and uncontrolled BP group (n=50) for retrospective study. HRR, HRV and clinical characteristics of the two groups were analyzed.Results Smoker, calcium antagonist use and combined drug treatment were significantly higher in the uncontrolled BP group than in the controlled BP group (P＜0.05). HRR and HRV values (rMSSD, pNN50, VLF, LF and HF) were significantly lower in the uncontrolled BP group than in the controlled BP group (P＜0.01). Multiple logistic regression analysis showed that lower HRV values (rMSSD, pNN50, VLF, LF and HF) were risk factors for BP control of hypertension after adjusting for smoker and calcium antagonist use. Conclusion The present results demonstrate that uncontrolled BP is associated with lower HRR and HRV values, suggesting that impaired autonomic nerve function is more serious in patients with uncontrolled hypertension.关键词
高血压病/心率恢复/心率变异性/自主神经功能Key words
hypertension/heart rate recovery/heart rate variability/autonomic nervous function分类
医药卫生引用本文复制引用
吴师伟,余意君,顾力,徐艳玲,吴慧君,郑伟,周志云,邹武松,顾晔..高血压病患者血压达标与自主神经功能的关系[J].广东医学,2019,40(5):671-675,5.基金项目
武汉市临床医学科研项目(西医类)(编号:WX16D24) （西医类）
