光学精密工程2019,Vol.27Issue(1):17-25,9.DOI:10.3788/OPE.20192701.0017
应用于内窥镜的聚酰亚胺涂覆双包层光纤束(英文)
Polyimide-coated fiber-optic bundle comprising double clad fibers for endoscopy
摘要
Abstract
A miniaturized (<0.4 mm), low-cost fiber bundle based endoscope suitable for pre-clinical research was presented.The device incorporates a Gradient-Index (GRIN) lens bonded to the proximal end of a fiber-optic image guide.Further, a simplified, low-cost connectorization method was proposed and connectorization for alternative applications was discussed.The fiber bundle was coated with polyimide which was bio-compatible for both long-and short-term implantation.In keeping with common laboratory and clinical procedures, the finished assembly allows for chemical cleaning, disinfection and autoclave sterilization with negligible impact on the overall performance of the device.The performance was evaluated by using standard test targets for white light as well as fluorescent micro-spheres to verify image quality.The results show that the effects of crosstalk between fibers and autofluroescence have a minimal impact on image quality.The fiber bundle assembly is able to resolve fluorescent samples at cellular resolution without the need for a complex optical path or laser scanning mechanism.关键词
光学诊断成像/光纤光学/内窥镜检查/渐变折射率透镜Key words
optical diagnostic imaging/fiber optics/endoscopy/gradient-index lens分类
信息技术与安全科学引用本文复制引用
萧恩,吴开杰,谷朝臣,关新平..应用于内窥镜的聚酰亚胺涂覆双包层光纤束(英文)[J].光学精密工程,2019,27(1):17-25,9.基金项目
国家重点科学仪器设备开发专项 (No.2013YQ03065101) (No.2013YQ03065101)
国家自然科学基金资助项目 (No.61503243) (No.61503243)