摘要
Abstract
Objective To analyze the effects of arsenious acid, dexamethasone and thalidomide in treatment of refractory multiple myeloma.Methods The 50 patients with refractory MM who were admitted to our hospital from June 2016 to June 2017 were selected as the research object, and they were divided into two groups, each with 25 cases.The control group was treated with thalidomide + dexamethasone.The observation group was treated with arsenic-acid, dexamethasone and thalidomide, and the results were analyzed.Results After the treatment of the two groups, there was a different degree of adverse reaction.Mainly for the digestive system reaction, loss of appetite, nausea and so on, severe vomiting.Secondly, liver function was impaired, and the detailed expression was alkaline phosphatase, bilirubin, and glutamate transaminase.The effective rate was 76.00 ％ in the control group and 92.00 ％ in the observation group.Compared with the control group, the treatment effect was significantly better in the observation group (P＜0.05).Conclusion For the refractory refractory multiple myeloma, use arsenite, dexamethasone and Sally amine combination therapy, can obtain satisfactory results, little adverse reaction, which will help prolong patient survival time, worthy of further promotion in clinical use.关键词
亚砷酸/地塞米松/沙利度胺/治疗难治性多发性骨髓瘤Key words
Arsenite/Dexamethasone/Thalidomide/Treatment of refractory multiple myeloma分类
医药卫生
