河南农业大学学报2019，Vol.53Issue(2)：213-217,5.
不同蜜环菌属真菌胞外多糖生物功能的研究
Study on bioactivities of extracellular polysaccharides of different genus of Armillaria
摘要
Abstract
In this study,11 species of Armillaria were taken as the research objects. The extracellular polysaccharides of 11 species were extracted from culture broth by liquid fermentation technology,and the yields of polysaccharides were determined by sulfuric acid-phenol method. The antitumor and antioxidant activities of extracellular polysaccharides were evaluated with HepG2 co-culture method and ferric reducing ability of plasma (FRAP) method, respectively. The results indicated that there were significant differences among the yields of extracellular polysaccharides with different species, from 0. 34 g·L - 1 to 9. 31 g·L - 1. In anti-tumor assays, the antiproliferative activities of extracellular polysaccharides from 11 species were remarkably different,and the polysaccharide of Armillaria luteopileata showed the most remarkable activities among all the species,with 253. 6 mg·L - 1 of IC50 value. The polysaccharide of Armillaria qinii showed the highest total antioxidant capacity in antioxidant assay,up to 976. 4 μmol·g - 1. Concerning the yields of extracellular polysaccharides, it was found that Armillar ia borealis was advantageous species with antitumor activity,and the Armillaria sinapina was the advantageous species in antioxidant effect.关键词
蜜环菌/发酵/胞外多糖/抗肿瘤/抗氧化Key words
Armillaria/fermentation/extracellular polysaccharide/anti-tumor/antioxidant分类
轻工纺织引用本文复制引用
赵爽,高宜,荣成博,苏哲,刘宇,马传贵,袁超,赵仲麟..不同蜜环菌属真菌胞外多糖生物功能的研究[J].河南农业大学学报,2019,53(2):213-217,5.基金项目
北京市农林科学院农产品加工与营养健康协同创新中心专项(KJCX201915) （KJCX201915）
北京市农林科学院科技创新能力建设专项 (KJCX20170205) （KJCX20170205）
