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典型Lewis-Sumner综合征临床分析

田海燕 滕军放 杨凌飞 孙亚娟 谢晶晶

中国实用神经疾病杂志2018,Vol.21Issue(22):2444-2449,6.
中国实用神经疾病杂志2018,Vol.21Issue(22):2444-2449,6.DOI:10.12083/SYSJ.2018.22.521

典型Lewis-Sumner综合征临床分析

Clinical analysis of Lewis-Sumner syndrome (LSS)

田海燕 1滕军放 1杨凌飞 1孙亚娟 1谢晶晶1

作者信息

  • 1. 郑州大学第一附属医院神经内科, 河南 郑州 450052
  • 折叠

摘要

Abstract

Objective To investigate the clinical features, Diagnosis, differential diagnosis and treatment of LSS and to increase the awareness of clinicians on LSS. Methods The clinical, biological and electrophysiological features, the course and the response to treatment of 8 typical cases of LSS were retrospectively analyzed and summarized. Results The eight patients included six males and two females, with the average age being 42. 6 years old. The initial symptoms started in the distal part of an upper limb in 62. 5 % of patients. They were exclusively sensory in 12. 5 % and sensorimotor in 87. 5 % of patients. A cranial nerve involvement was observed in 12. 5 % of patients and a distal limb amyotrophy in 25 %. Electrophysiological study showed conduction block (CB). The 75 % of patients achieved clinical recovery with immunoglobulin, hormone shock and improve the microcirculation, nutritional nerves and other treatment. Conclusion LSS is an immune-mediated disease that can be diagnosed by serological, cerebrospinal fluid, and neurophysiological examinations. Early detection, early diagnosis, and early treatment can promote a better prognosis.

关键词

Lewis-Sumner综合征/非对称性/传导阻滞/免疫治疗/慢性脱髓鞘性多发性神经根神经病

Key words

Objective Lewis-Sumner syndrome/Asymmetrical/Conduction block/Immunity therapy/Chronic inflammatory demyelinating polyneuropathy

分类

医药卫生

引用本文复制引用

田海燕,滕军放,杨凌飞,孙亚娟,谢晶晶..典型Lewis-Sumner综合征临床分析[J].中国实用神经疾病杂志,2018,21(22):2444-2449,6.

中国实用神经疾病杂志

1673-5110

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