摘要
Abstract
Objective To observe the effect of cranial electrotherapy stimulation (CES) combined with escitalopram on quality of life and activities of daily living of patients with depression after cerebral infarction (PSD).Methods 160 patients with PSD admitted to the Neurology Department of Luoyang Rongkang Hospital from February 2014 to February 2016 were randomly divided into the control group and the observation group, with 80 cases in each group.Both groups were given conventional treatments, such as regulating blood glucose and blood lipids, controlling blood pressure, maintaining water-salt balance and improving cerebral circulation and psychological counseling.The control group was treated with additional escitalopram, while the observation group was treated with escitalopram combined with CES.The quality of life, depression, neurological impairment and activities of daily living of patients were evaluated with the World Health Organization Quality of Life Questionnaire abbreviated version (WHOQOL-BREF), the Hamilton Depression Scale (HAMD), the modified Edinburgh-Scandinavia Stroke Scale (MESSS) and the modified Barthel Index (MBI), respectively. Results There was no significant difference in the scores of quality of life or the total score between the two groups before treatment (P＜0. 05).After treatment, the scores of quality of life and the total scores of the two groups increased significantly (P＜0. 05), and those of the observation group were significantly higher than those of the control group (P＜0. 05).Before treatment, there was no significant difference in scores of HAMD, MESS, or MBI between the two groups (P＞ 0. 05). After treatment, the scores of HAMD, MESS and MBI of both groups decreased significantly (P ＜0. 05), and the scores of observation group were significantly lower than those of the control group (P＜0. 05).Conclusion CES combined with escitalopram can significantly improve the quality of life and activities of daily living of patients with PSD.The curative effect is better than that of escitalopram alone.关键词
经颅微电流刺激/艾司西酞普兰/脑梗死后抑郁/生活质量/生活能力Key words
Cranial electrotherapy stimulation/Escitalopram/Depression after cerebral infarction/Quality of life/Activities of daily living分类
医药卫生
