华西口腔医学杂志2019,Vol.37Issue(1):102-105,4.DOI:10.7518/hxkq.2019.01.020
组蛋白乙酰化在慢性牙周炎来源牙周膜干细胞成骨分化中的作用
Effect of histone acetylation on osteogenic differentiation of periodontal ligament stem cells derived from periodontitis tissue
摘要
Abstract
Epigenetics is defined as a change in gene expression without the alteration of the genetic sequence.Such a change would be inherited by offspring.Histone acetylation is a type of epigenetics.Existing studies proposed that chronic periodontitis is related to epigenetic modification.In this review, we summarised the influence of chronic periodontitis on periodontal ligament stem cells by histone acetylation.关键词
组蛋白乙酰化/慢性牙周炎/牙周膜干细胞/成骨分化Key words
histone acetylation/chronic periodontitis/periodontal ligament stem cells/osteogenic differentiation分类
生物科学引用本文复制引用
孙晋,刘芸,屈茜,曲娟,罗纬,张锋,吴敏..组蛋白乙酰化在慢性牙周炎来源牙周膜干细胞成骨分化中的作用[J].华西口腔医学杂志,2019,37(1):102-105,4.基金项目
深圳市科创委立项 (JCYJ20160427191204874) (JCYJ20160427191204874)
中国疾病预防控制中心妇幼保健中心合生元母婴营养与健康研究项目 (20-18FYH013) (20-18FYH013)