中国当代医药2019,Vol.26Issue(11):30-33,4.
生物钟紊乱导致护士患乳腺癌风险的研究进展
Research progress on the risk of breast cancer in nurses caused by biological clock disorder
田维艳 1黎琪 2张晓娇 1蒲亨萍3
作者信息
- 1. 遵义医科大学研究生院,贵州 遵义 563000
- 2. 遵义医科大学附属医院急诊科,贵州 遵义 563002
- 3. 遵义医科大学第三附属医院 遵义市第一人民医院,贵州 遵义 563002
- 折叠
摘要
Abstract
Most organisms have biological clocks, also known as biological rhythms, human beings are no exception, but external environmental stimuli can strengthen, weaken or even destroy this rhythm. Because of the particularity of nursing profession, nurses carry out shift system, and irregular shift will break the daily life and rest and lead to the reversal of day and night and the disorder of biological rhythm. Animal experiments and population epidemiological studies show that the disorder of biological rhythm is associated with the risk of breast cancer, but its mechanism has not been determined. Now it is more studied that the negative feedback circulatory disorder and circadian rhythm disorder caused by the autonomic regulation of many biological clock genes lead to abnormal hormone levels in the body. In this paper, the relationship among irregular shift, biological rhythm disorder and breast cancer was reviewed in order to provide basis for nursing managers to work on shifts, to prevent breast cancer risk for nurses and to improve their physical and mental health.关键词
生物钟紊乱/轮班制/褪黑素/乳腺癌/护士Key words
Circadian clock disorder/Shift system/Melatonin/Breast cancer/Nurse分类
医药卫生引用本文复制引用
田维艳,黎琪,张晓娇,蒲亨萍..生物钟紊乱导致护士患乳腺癌风险的研究进展[J].中国当代医药,2019,26(11):30-33,4.