中国当代医药2019，Vol.26Issue(11)：58-60,3.
津力达颗粒对冠心病合并2 型糖尿病患者血管内皮功能的影响
Effect of Jinlida Granule on vascular endothelial function in patients with coronary heart disease complicated with type 2 diabetes mellitus
摘要
Abstract
Objective To investigate the effect of Jinlida Granule on vascular endothelial function in patients with coronary heart disease complicated with type 2 diabetes mellitus. Methods A total of 73 patients with coronary heart disease complicated with type 2 diabetes mellitus admitted to our hospital from March 2017 to March 2018 were selected as the study subjects, according to the random number table method, they were divided into observation group (43 cases) and control group (30 cases). The control group was treated with routine western medicine and oral hypoglycemic drugs or insulin according to blood sugar, the observation group was treated with Jinlida Granule on the basis of the above treatment. The levels of fasting blood glucose and vascular endothelial function indexes before and after treatment were compared between the two groups: vascular endothelial growth factor (VEGF), endothelin-1 (ET-1), nitric oxide (NO). Results The levels of fasting blood sugar and ET-1 after treatment in both groups were lower than those before treatment, and the levels of vascular endothelial growth factor and nitric oxide were higher than those before treatment, the differences were statistically significant (P<0.05). The levels of fasting blood sugar and ET-1 in the observation group were lower than those in the control group, and the levels of vascular endothelial growth factor and nitric oxide in the observation group were higher than those in the control group, the differences were statistically significant (P<0.05). Conclusion Jinlida Granule can effectively cooperate with western medicine to reduce blood sugar level, improve vascular endothelial function, and effectively improve the occurrence and development of coronary heart disease complicated with type 2 diabetes mellitus.关键词
津力达颗粒/冠心病合并2 型糖尿病/血管内皮功能/影响Key words
Jinlida Granule/Coronary heart disease complicated with type 2 diabetes mellitus/Vascular endothelial function/Effect分类
医药卫生引用本文复制引用
杨丽,程奎,胡淑芳..津力达颗粒对冠心病合并2 型糖尿病患者血管内皮功能的影响[J].中国当代医药,2019,26(11):58-60,3.基金项目
湖北省武汉市卫生和计划生育委员会科研项目(WZ16C22) （WZ16C22）
