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胸腺五肽联合奥沙利铂和卡培他滨方案在直肠癌术后患者辅助化疗中的应用效果

黄水仙 蔡徐杰 吴江洪 赖珍苗

中国当代医药2019,Vol.26Issue(11):64-66,3.
中国当代医药2019,Vol.26Issue(11):64-66,3.

胸腺五肽联合奥沙利铂和卡培他滨方案在直肠癌术后患者辅助化疗中的应用效果

Application effect of Thymopentin combined with Oxaliplatin and Capecitabine in adjuvant chemotherapy for patients with rectal cancer

黄水仙 1蔡徐杰 2吴江洪 3赖珍苗1

作者信息

  • 1. 广东省英德市人民医院药学部,广东 英德 513000
  • 2. 广东省英德市人民医院肿瘤科,广东 英德 513000
  • 3. 广东省英德市中医院肿瘤科,广东 英德 513000
  • 折叠

摘要

Abstract

Objective To investigate the application effect of Thymopentin combined with Oxaliplatin and Capecitabine in adjuvant chemotherapy for patients with rectal cancer. Methods Fifty patients with rectal cancer admitted to Yingde People's Hospital from August 2016 to June 2018 were selected as the study subjects, they were divided into control group and observation group according to random number table method, with 25 cases in each group. The control group was treated with Oxaliplatin combined with Capecitabine, while the observation group was treated with Thymopentin on the basis of the control group. The blood routine and quality of life scores were compared between the two groups. Results The leucocyte count in the observation group was significantly higher than that in the control group, the difference was significant (P<0.05). After chemotherapy, the scores of mood, sleep and appetite in the observation group were significantly lower than those in the control group, and the KPS scores were significantly higher than those in the control group, the differences were significant (P<0.05). Conclusion Chemotherapy with Thymopentin combined with Oxaliplatin and Capecitabine can significantly improve the quality of life of patients with rectal cancer and the bone marrow suppression caused by chemotherapy.

关键词

胸腺五肽/卡培他滨/奥沙利铂/直肠癌/化疗

Key words

Thymopentin/Capecitabine/Oxaliplatin/Rectal cancer/Chemotherapy

分类

医药卫生

引用本文复制引用

黄水仙,蔡徐杰,吴江洪,赖珍苗..胸腺五肽联合奥沙利铂和卡培他滨方案在直肠癌术后患者辅助化疗中的应用效果[J].中国当代医药,2019,26(11):64-66,3.

基金项目

广东省清远市社会发展领域自筹经费科技计划项目(2015B098) (2015B098)

中国当代医药

1674-4721

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