中国当代医药2019，Vol.26Issue(11)：83-85,3.
不同化疗方案联合调强放疗对鼻咽癌预后的效果比较
Effect comparison of different chemotherapy regimens combined with intensity modulated radiotherapy on the prognostic of nasopharyngeal carcinoma
摘要
Abstract
Objective To explore the effect of different chemotherapy regimens combined with intensity modulated radiation therapy on the prognosis of nasopharyngeal carcinoma. Methods A total of 219 patients with nasopharyngeal carcinoma admitted in our hospital from January to December 2016 were selected as the study subjects, they were divided into control group (108 cases) and research group (111 cases) according to the principle of random sampling. The control group was treated with Docetaxel combined with Cisplatin, while the study group was treated with Docetaxel combined with Nedaplatin, all of which were treated with intensity-modulated radiotherapy. The incidence of adverse reactions and overall survival were compared between the two groups. Results The incidence of gastrointestinal reactions in the study group (10.81％) was lower than that in the control group (21.30％), the difference was statistically significant (P<0.05). There were no significant differences in the incidence of bone marrow suppression, radiation oral mucositis and mild liver injury between the two groups (P>0.05). There was no significant difference in overall survival rate between the two groups after 6 months of treatment (P>0.05). Conclusion Docetaxel combined with Nedaplatin and intensity modulated radiotherapy for nasopharyngeal carcinoma patients overall survival is good, comparable to docetaxel combined with cisplatin, can reduce the gastrointestinal reaction of patients.关键词
不同化疗方案/调强放疗/鼻咽癌/不良反应Key words
Different chemotherapy regimens/Intensity modulated radiotherapy/Nasopharyngeal carcinoma/Adverse reactions分类
医药卫生引用本文复制引用
钟琼,吴仁瑞,黄俊骢,廖晓红,陈元平..不同化疗方案联合调强放疗对鼻咽癌预后的效果比较[J].中国当代医药,2019,26(11):83-85,3.基金项目
江西省卫生健康委科技计划(指导性计划)项目(20197381) （指导性计划）
