中国健康心理学杂志2019，Vol.27Issue(2)：161-165,5.DOI:10.13342/j.cnki.cjhp.2019.02.001
抑郁症患者睡眠质量与神经认知的相关研究
The relationship between sleep and neurocognitive in depressive disorder
摘要
Abstract
Objective:To compare the quality of sleep and the level of neurocognitive between patients with depression and healthy controls, and to explore their relationship between the quality of sleep and the level of neurocognitive and emotional symptoms.Methods:Forty-three patients with depression and thirty-one healthy subjects were assessed with Pittsburgh sleep quality index (PSQI) , Athens Insomnia Scale (AIS) , Trail Marking Test (TMT) , Digit Span Test (DST) , Verbal Fluency Test (VLT) , Montreal Cognitive Assessment (MoCA) , Stoop Color-Word Test (SCWT) and Auditory Verbal Learning Test (AVLT) .Meanwhile, the patients with depression were also assessed by Hamiltion Anxiety Scale (HAMA) and Hamiltion Depreesion Scale (HAMD) .Results:The total score of PSQI and the score of AIS in patients with depression were higher than those of healthy subjects (Z=-5.914, -6.120;P<0.01) .Compared with the healthy controls, patients with depression had significantly higher scores of TMT-B (Z =-2.405, P<0.05) , had significantly lower scores of immediate memory and delayed memory in AVLT (Z=-3.324, -2.710, P<0.01) .Correlation analysis showed that the total score of PSQI and the score of AIS were significantly positive correlated with the scores of HAMA and HAMD in the patients group (r=0.3270.466, P<0.05) .The total scores of PSQI were significantly negatively correlated with the total scores of MoCA (r=-0.433, P<0.01) , and had statistically significant trend with the scores of VLT and TMT-A;The scores of AIS had statistically significant trend with the total scores of MoCA.After control of the scores of HAMA and HAMD, there also had significant correlation between the total score of PSQI and MoCA (r=-0.387, P<0.05) .Conclusion:Patients with depression have sleep disorder and neurocognitive impairment.There is a correlation between the quality of sleep and the level of neurocognitive, and the correlation is independent with anxiety depression symptoms.关键词
神经认知/睡眠/焦虑/抑郁/抑郁症Key words
Neurocognitive/Sleep/Anxiety/Depression/Depression disorder分类
医药卫生引用本文复制引用
杨德英,方文梅,李慧,朱道民,董毅..抑郁症患者睡眠质量与神经认知的相关研究[J].中国健康心理学杂志,2019,27(2):161-165,5.基金项目
安徽省合肥市科技攻关项目(编号:JZ201512250007) （编号:JZ201512250007）
