解剖学杂志(社会科学版)2019，Vol.42Issue(2)：167-172,6.DOI:10.3969/j.issn.1001-1633.2019.02.013
快肌与慢肌失神经支配后的形态学变化
Morphological changes of denervated fast-twitch and slow-twitch muscles
摘要
Abstract
Objective:To investigate the morphological differences between fast-twitch muscles(tibialis anterior)and slow-twitch muscles(soleus)during denervation.Methods:The rat sciatic nerve disconnection model was established,and the morphological changes of the tibialis anterior and soleus muscles during denervation were analyzed by histopathological techniques.Results:After sciatic nerve injury,soleus atrophy was more severe compared to tibialis anterior muscle,as evidenced by smaller wet weight,lower cross-sectional area ratio of muscle fiber,less complete ultrastructure and more serious damage of motor endplate.Conclusion:The atrophy of slow-twitch muscle is more severe than fast-twitch muscle after denervation.关键词
神经损伤/快肌/慢肌/失神经支配/肌萎缩Key words
nerve injury/fast-twitch muscle/slow-twitch muscle/denervation/muscular atrophy引用本文复制引用
沈筠恬,喻妙梅,仇嘉颖,孙华林,丁斐..快肌与慢肌失神经支配后的形态学变化[J].解剖学杂志(社会科学版),2019,42(2):167-172,6.基金项目
国家自然科学基金(81671230,81301628) （81671230,81301628）
国家973计划课题(2014CB542202,2014CB542203) （2014CB542202,2014CB542203）
中国博士后基金(2016M591894) （2016M591894）
江苏省博士后基金(1601040A) （1601040A）
南通大学博士启动基金(15B18,17ZZ040) （15B18,17ZZ040）
